NDLI: Use of near-infrared spectroscopy as a physiologic monitor for intra-abdominal hypertension.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Widder, Sandy Ranson, Michael K. Zygun, David Knox, Linda Laupland, Kevin B. Laird, Philip Ball, Chad G. Kirkpatrick, Andrew W.
Description	Country affiliation: Canada Author Affiliation: Widder S ( Regional Trauma Services, Foothills Medical Centre, Calgary, Alberta, Canada.)
Abstract	BACKGROUND: Intra-abdominal hypertension (IAH) is increasingly recognized as an important parameter in critically ill (ICU) patients. IAH affects perfusion to all abdominal components including the abdominal wall (AW). Near infrared spectroscopy (NIRS) measures changes in three chromophores including oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (Hb), and cytochrome aa3 (Cyt), providing information concerning dysoxia. We sought to examine whether NIRS measurement of the AW was safe, and correlated with intra-abdominal pressure (IAP) in ICU patients. METHODS: A NIU-Pro001 system recorded NIRS data over 24 hours from the AW of 9 ICU patients at risk for IAH. IAP was recorded from the bladder. Changes in chromophore values are interpolated from best-fit polynomial curves. RESULTS: Sixty-six paired IAP and NIRS readings were taken from 9 ICU (4-12 observations/patient) patients. No measurement related adverse reactions occurred. The mean (range) first values measured in these patients were; IAP 17.2 mm Hg (9-31); HbO2 0.41 micromol/L (-8.4 to 7.6); Hb 2.6 micromol/L (-3.1 to 12.2); and Cyt 0.65 micromol/L (-3.4 to 4.8). A significant, inverse (or negative) association was found between DeltaNIRS HbO2 level and DeltaIAP (coefficient, -0.1588; p = 0.008). No association was found between DeltaNIRS Hb or DeltaCyt and DeltaIAP. CONCLUSION: NIRS of the AW appears safe. NIRS measurement of changes in HbO2 appears to be associated with DeltaIAP, and warrant further study in greater numbers of ICU patients with more frequent IAP readings, over longer periods of critical illness.
File Format	HTM / HTML
ISSN	00225282
Issue Number	5
Volume Number	64
e-ISSN	15298809
Journal	The Journal of Trauma: Injury, Infection, and Critical Care
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2008-05-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Hypertension Research Support, Non-u.s. Gov't Intensive Care Units Clinical Trial Wounds And Injuries Humans Middle Aged Mortality Male Aged, 80 And Over Pressure Discipline Traumatology Journal Article Abdomen Monitoring, Physiologic Compartment Syndromes Classification Female Spectroscopy, Near-infrared Aged Methods
Content Type	Text
Resource Type	Article
Subject	Surgery Critical Care and Intensive Care Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in