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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Huh, Jung Wook Kim, Hyeong Rok Kim, Young Jin |
| Description | Author Affiliation: Huh JW ( Department of Surgery, Chonnam National University, Hwasun Hospital and Medical School, Gwangju, Korea.) |
| Abstract | BACKGROUND: The aim of this study was to evaluate whether the use of fibrin glue as a sealant over an anastomosis is a risk factor for anastomotic leakage after laparoscopic rectal cancer surgery. METHODS: Prospective data were collected from 223 patients with rectal cancer who underwent laparoscopic resection without defunctioning stoma. RESULTS: A total of 104 patients underwent laparoscopic rectal resection, followed by the application of fibrin glue over the stapled anastomosis, while 119 underwent surgery alone. No difference in clinically significant leakage was observed between the fibrin and the nonfibrin groups (5.8% vs 10.9%, P = .169). In multivariate analysis, extraperitoneal tumor location and operation duration >220 minutes were independently associated with anastomotic leakage. CONCLUSIONS: Significant predictors of anastomotic leakage include extraperitoneal tumor location and operation length >220 minutes. Fibrin glue application over the stapled anastomosis was not found to be significantly associated with anastomotic leakage. |
| File Format | HTM / HTML |
| ISSN | 00029610 |
| Issue Number | 4 |
| Volume Number | 199 |
| e-ISSN | 18791883 |
| Journal | The American Journal of Surgery |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-04-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Therapy Multivariate Analysis Prospective Studies Humans Middle Aged Surgical Staplers Male Fibrin Tissue Adhesive Journal Article Discipline General Surgery Time Factors Etiology Surgery Adult Female Tissue Adhesives Odds Ratio Risk Factors Treatment Outcome Laparoscopy Aged, 80 And Over Therapeutic Use Pathology Rectal Neoplasms Anastomosis, Surgical Aged Neoplasm Staging Surgical Wound Dehiscence |
| Content Type | Text |
| Resource Type | Article |
| Subject | Surgery |
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