NDLI: Principes oncologiques du contrôle local de la tumeur primitive.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Soulié, M. Portier, G. Salomon, L.
Description	Author Affiliation: Soulié M ( Département d'urologie-andrologie-transplantation rénale, CHU Rangueil, 1, avenue Jean-Poulhès, 31059 Toulouse cedex 9, France. Electronic address: soulie.m@chu-toulouse.fr.); Portier G ( Service de chirurgie digestive, CHU Purpan, place Baylac, 31059 Toulouse cedex 9, France.); Salomon L ( Service d'urologie et de transplantation rénale et pancréatique, CHU Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France.)
Abstract	OBJECTIVE: Review of the databases of carcinogenesis and the principles of local control of the primary tumor in order to decrease the risk of tumor progression and predict metastatic behavior. MATERIALS AND METHODS: Review of the literature using Medline databases based on scientific relevance. Research was centered on the characteristics of solid tumor development, the basics of local control of the primary tumor, latest advance in genomics and the oncological principles applied on prostate cancer surgery. RESULTS: The cornerstone in order to cure a local or locally advanced cancer is to eradicate the primary tumor. This should be done using effective methods that can assure local control, decrease the risk of progression and metastasis. The oncological surgery is the most important step in order to have this tumor control, beside radiotherapy and systemic therapy associated. In localized prostate cancer, surgery remains the gold standard between the multiple therapeutic modalities proposed. CONCLUSION: The local control of solid malignant tumor is primordial in order to change the natural history of the disease and decrease its risk of progression. This is the goal of oncological surgery, and starting from these principles radical prostatectomy was favored.
File Format	HTM / HTML
ISSN	11667087
Issue Number	15
Journal	Progr`es en Urologie
Volume Number	25
Language	French
Publisher	Elsevier
Publisher Date	2015-11-01
Publisher Place	France
Access Restriction	Subscribed
Subject Keyword	Therapy Medical Oncology Pathology Discipline Urology Humans Review Neoplasms Disease Progression English Abstract Journal Article
Alternative Title	Oncological principles for local control of primary tumor
Content Type	Text
Resource Type	Article
Subject	Urology

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