NDLI: Sudden Pediatric Hearing Loss: Comparing the Results of Combined Treatment (Intratympanic Dexamethasone and Systemic Steroids) With Systemic Steroid Treatment Alone.

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Sudden Pediatric Hearing Loss: Comparing the Results of Combined Treatment (Intratympanic Dexamethasone and Systemic Steroids) With Systemic Steroid Treatment Alone.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Övet, Gültekin Alatas, Necat Güzelkara, Fatih
Description	Country affiliation: Turkey Author Affiliation: Övet G ( Medical Sciences University, Training and Research Hospital, Department of Otorhinolaryngology, Konya, Turkey.)
Abstract	OBJECTIVE: The aim of the present study was to compare hearing improvements obtained with combined intratympanic and systemic steroid therapy, and systemic steroid therapy alone in pediatric patients with idiopathic sudden sensorineural hearing loss (SSHL). STUDY DESIGN: Retrospective. SETTING: Tertiary referral hospital. PATIENTS: Pediatric patients with SSHL. INTERVENTIONS: The patients were divided into two groups, based on the method of steroid administration: Group 1 (systemic therapy group, nâ=â23) was treated with oral methylprednisolone alone whereas Group 2 (combination therapy group, nâ=â26) was treated with combination of oral methylprednisolone and intratympanic dexamethasone injections. MAIN OUTCOME MEASURES: Pre- and post-treatment audiograms were compared with pure-tone averages (PTAs) in each group. Two treatment groups were also compared. The final hearing assessment was performed 4 weeks after completion of the treatment. RESULTS: The mean PTAs before and after the treatment were 61.86â±â23.99 and 42.65â±â32.69âdB in Group 1 (pâ=â0.001), and 70.07â±â29.74 and 38.85â±â32.28âdB in Group 2 (pâ=â0.001). Pure-tone gain was 20.00â±â15.02âdB in Group 1, and 31.69â±â28.29âdB in Group 2. Comparison of two groups for post-treatment PTA and pure-tone gains did not yield any statistically significant differences (pâ=â0.388 and pâ=â0.132, respectively). CONCLUSION: Significant hearing improvement may be obtained with use of systemic steroids alone, or simultaneous administration of systemic and intratympanic steroids in pediatric patients with SSHL. Although we did not have a control group, two treatment options appear to offer similar hearing improvements in the pediatric age group higher than the rates obtained with placebo when previous studies in the literature are taken into account.
File Format	HTM / HTML
ISSN	15317129
Issue Number	6
Journal	Otology & Neurotology
Volume Number	37
e-ISSN	15374505
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2016-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Otolaryngology
Content Type	Text
Resource Type	Article
Subject	Otorhinolaryngology Sensory Systems Neurology (clinical)

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