NDLI: Prevalence and Severity of Dysphonia in Patients with Cystic Fibrosis: A Pilot Study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Willis, John Michael, Deirdre D. Boyer, Holly Misono, Stephanie
Description	Country affiliation: United States Author Affiliation: Willis J ( Lions Voice Clinic, Department of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.); Michael DD ( Lions Voice Clinic, Department of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.); Boyer H ( Lions Voice Clinic, Department of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.); Misono S ( Lions Voice Clinic, Department of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA smisono@umn.edu.)
Abstract	OBJECTIVE: To assess the prevalence and severity of dysphonia in patients with cystic fibrosis sinusitis. We hypothesized that patients with CF sinusitis, compared with 2 control groups, would have higher self-reported prevalence of dysphonia and greater severity of dysphonia, according to patient-reported outcome measures as well as auditory-perceptual evaluation by expert listeners. STUDY DESIGN: Cross-sectional comparative pilot study. SETTING: Academic tertiary care clinic. STUDY PARTICIPANTS AND METHODS: Analysis included 37 study participants: 17 patients with CF sinusitis, 10 healthy individuals, and 10 patients with non-CF sinusitis. All participants completed the 10-item Voice Handicap Index (VHI-10) questionnaire and provided voice samples. On all samples, 6 blinded speech-language pathologists independently performed auditory-perceptual evaluation, using Consensus Auditory-Perceptual Evaluation of Voice. To assess severity of sinonasal symptoms, we used the 20-item Sinonasal Outcome Test (SNOT-20). Standard parametric and nonparametric statistical analysis was performed. RESULTS: The differences between the 3 groups in prevalence of abnormal VHI-10 scores were not statistically significant. SNOT-20 scores were similar in the 2 sinusitis patient groups. VHI-10 scores were highest in patients with CF sinusitis, intermediate in patients with non-CF sinusitis, and lowest in healthy individuals (P = .005). Auditory-perceptual evaluation demonstrated greater overall severity of dysphonia in patients with CF sinusitis compared with the 2 control groups (P = .0005). CONCLUSIONS: Cystic fibrosis sinusitis appeared to be associated with worse vocal function as measured by patient self-report as well as auditory-perceptual evaluation of voice compared with patients with non-CF sinusitis and healthy controls. Further investigation in this area is warranted.
File Format	HTM / HTML
ISSN	01945998
Issue Number	1
Volume Number	153
e-ISSN	10976817
Journal	Otolaryngology -- Head and Neck Surgery
Language	English
Publisher	SAGE Publications
Publisher Date	2015-07-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Cross-sectional Studies Prevalence Humans Middle Aged Speech Production Measurement Male Epidemiology Sinusitis Journal Article Young Adult Case-control Studies Outcome Assessment (health Care) Questionnaires Dysphonia Adult Female Speech Intelligibility Diagnosis Severity Of Illness Index Cystic Fibrosis Complications Discipline Otolaryngology Pilot Projects Adolescent
Content Type	Text
Resource Type	Article
Subject	Otorhinolaryngology Surgery

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