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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Chang, Jae Won Hong, Hyun Jun Ban, Myung Jin Shin, Yoo Seob Kim, Won Shik Koh, Yoon Woo Choi, Eun Chang |
| Description | Author Affiliation: Chang JW ( Department of Otolaryngology-Head and Neck Surgery, Cancer Research Institute, Research Institute for Medical Sciences, Chungnam National University College of Medicine, Daejeon, Republic of Korea.); Hong HJ ( Department of Otolaryngology, International St Mary's Hospital, Incheon, Republic of Korea.); Ban MJ ( Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.); Shin YS ( Department of Otolaryngology, Ajou University School of Medicine, Suwon, Republic of Korea.); Kim WS ( Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.); Koh YW ( Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.); Choi EC ( Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea EUNCHANGMD@yuhs.ac.) |
| Abstract | OBJECTIVE: To investigate the treatment outcomes of parotid gland cancer at a single center over a 10-year period and to evaluate the prognostic significance of maximum standardized uptake value. STUDY DESIGN: Retrospective case series with chart review. SETTING: Academic care center. SUBJECTS AND METHODS: Ninety-eight patients with primary parotid gland cancer who were surgically treated at Yonsei University Head & Neck Cancer Clinic between January 1999 and December 2008 were analyzed. Patient data were collected retrospectively from medical charts. The investigators analyzed the association of clinicopathological factors and maximum standardized uptake value on (18)F-fluorodeoxyglucose positron emission tomography-computed tomography scan with disease-specific survival. RESULTS: Mean patient age was 49.7 years. Mean follow-up was 48.8 months. Thirty-three, 40, 30, and 23 patients had stage I, II, III, and IVA disease, respectively. Mucoepidermoid carcinoma was the most common histologic type (34.7%), followed by acinic cell carcinoma (27.6%). Eighteen patients (18.4%) experienced recurrences (mean recurrence gap, 20.6 months; range, 2-87 months). Five- and 10-year disease-specific survival rates were 93.6% and 81.8%, respectively. In the univariate analysis, pathologic T stage, pathologic lymph node status, resection margin, external parenchymal extension, and maximum standardized uptake value were significantly associated with disease-specific survival. Pathologic lymph node status and maximum standardized uptake value were independent prognostic factors in the multivariate analysis. CONCLUSION: Our single-center experience with parotid gland cancer treatment is consistent with the literature. Cervical lymph node metastasis and high maximum standardized uptake value are associated with poor survival in parotid gland cancer. |
| File Format | HTM / HTML |
| ISSN | 01945998 |
| Issue Number | 6 |
| Volume Number | 153 |
| e-ISSN | 10976817 |
| Journal | Otolaryngology -- Head and Neck Surgery |
| Language | English |
| Publisher | SAGE Publications |
| Publisher Date | 2015-12-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Carcinoma, Mucoepidermoid Prognosis Tomography, Emission-computed Mortality Humans Middle Aged Neoplasm Recurrence, Local Discipline Otolaryngology Male Treatment Outcome Lymphatic Metastasis Aged, 80 And Over Journal Article Parotid Neoplasms Surgery Adolescent Adult Carcinoma, Acinar Cell Female Fluorodeoxyglucose F18 Aged Retrospective Studies Diagnosis Child |
| Content Type | Text |
| Resource Type | Article |
| Subject | Otorhinolaryngology Surgery |
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