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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ludwig, Endre Jorgensen, Lindsay Gray, Sharon Munson, Samantha Chou, Kathy Gutterman, Elane M. |
| Spatial Coverage | Hungary |
| Description | Author Affiliation: Ludwig E ( Semmelweis Egyetem II. Belgyógyászati Klinika, Infektológiai Tanszéki Csoport Budapest Gyáli út 5-7. 1097.); Jorgensen L ( Via Research Princeton Junction NJ USA.); Gray S ( Pfizer, Inc. Collegeville PA USA.); Munson S ( Pfizer, Inc. Collegeville PA USA.); Chou K ( Via Research Princeton Junction NJ USA.); Gutterman EM ( Via Research Princeton Junction NJ USA.) |
| Abstract | INTRODUCTION: Assessment of the impact of pneumococcal conjugate vaccines on the burden of pneumonia, meningitis, and septicemia in Hungary is limited. AIM: The aim of this retrospective study was to quantify rates of hospitalized multi-cause and pneumococcal pneumonia, meningitis, and septicemia in all age groups in Hungary between 2006 and 2011. METHOD: Aggregate data were obtained from the Hungarian National Healthcare Fund using pre-specified ICD-10 codes. Comparisons included average rates pre-vaccine (2006-2007) versus post-vaccine (2010-2011) using a χ2 test. RESULTS: Hospitalization rates among children aged 0-4 years significantly declined for multi-cause pneumonia and meningitis, but increased for septicemia. There were significant increases in multi-cause pneumonia and septicemia in other age groups. In-hospital mortality rates increased with age. Limited use of pneumococcal-specific codes led to inconclusive findings for pneumococcal diseases. CONCLUSIONS: Declines in multi-cause pneumonia and meningitis in children aged 0-4 years suggest direct effects of pneumococcal conjugate vaccination on hospitalization rates. |
| File Format | HTM / HTML |
| ISSN | 00306002 |
| e-ISSN | 17886120 |
| Journal | Orvosi Hetilap |
| Issue Number | 36 |
| Volume Number | 155 |
| Language | Hungarian |
| Publisher | Markusovszky Lajos |
| Publisher Date | 2014-09-07 |
| Publisher Place | Hungary |
| Access Restriction | Open |
| Subject Keyword | Mass Vaccination Pneumonia Age Distribution Comparative Study Microbiology Child, Preschool Infant Pneumonia, Pneumococcal Epidemiology Pneumococcal Vaccines Meningitis Vaccines, Conjugate Discipline Medicine Retrospective Studies International Classification Of Diseases Streptococcus Pneumoniae Meningitis, Pneumococcal Hospital Mortality Hungary Isolation & Purification Hospitalization Administration & Dosage Bacteremia Adolescent Cost Of Illness Statistics & Numerical Data |
| Alternative Title | Clinical burden of multi-cause and pneumococcal pneumonia, meningitis, and septicemia in Hungary. Results of a retrospective study (2006-2011) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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