NDLI: Clinical evaluation of Moro (Citrus sinensis (L.) Osbeck) orange juice supplementation for the weight management.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Cardile, Venera Graziano, Adriana Carol Eleonora Venditti, Alessandro
Description	Country affiliation: Italy Author Affiliation: Cardile V ( a Section of Physiology, Department of Bio-Medical Sciences , University of Catania , Viale Andrea Doria 6, 95125 Catania , Italy.); Graziano AC ( a Section of Physiology, Department of Bio-Medical Sciences , University of Catania , Viale Andrea Doria 6, 95125 Catania , Italy.); Venditti A ( b Dipartimento di Chimica , 'Sapienza' Università di Roma , Piazzale Aldo Moro 5, 00185 Roma , Italy.)
Abstract	In the last years, several studies have recently evaluated the beneficial effects of red orange juice (Citrus sinensis (L.) Osbeck) and its active components in weight management and obesity. Moro orange is a cultivar of red orange, particularly rich in active compounds such as anthocyanins, hydroxycinnamic acids, flavone glycosides and ascorbic acid, which displays anti-obesity effects in in vitro and in vivo studies. In this clinical study, the effect of a Moro juice extract (Morosil(®), 400 mg/die) supplementation was evaluated in overweight healthy human volunteers for 12 weeks. Results showed that Moro juice extract intake was able to induce a significant reduction in body mass index (BMI) after 4 weeks of treatment (p < 0.05). Moreover, in subjects treated with Moro extract, body weight, BMI, waist and hip circumference were significantly different from the placebo group (p < 0.05). In conclusion, it could be suggested that the active compounds contained in Moro juice have a synergistic effect on fat accumulation in humans and Moro juice extract can be used in weight management and in the prevention of human obesity.
File Format	HTM / HTML
ISSN	14786419
Issue Number	23
Volume Number	29
e-ISSN	14786427
Journal	Natural Product Research
Language	English
Publisher	Taylor & Francis
Publisher Date	2015-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Body Mass Index Discipline Natural products Citrus Sinensis Fruit And Vegetable Juices Plant Extracts Humans Middle Aged Drug Therapy Discipline Natural Products Double-blind Method Pharmacology Randomized Controlled Trial Journal Article Overweight Young Adult Waist Circumference Weight Loss Adult Dietary Supplements
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Plant Science Analytical Chemistry Biochemistry

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