NDLI: Effectiveness of a prematurity-based protocol for management of infants born to mothers with Group B Streptococcus colonisation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Zuppa, A. A. Alighieri, G. Fracchiolla, A. Galluccio, C. Riccardi, R. Cavani, M. Romagnoli, C.
Spatial Coverage	Italy
Description	Country affiliation: Italy Author Affiliation: Zuppa AA ( Department of Pediatrics, Division of Neonatology, Catholic University of the Sacred Heart , Rome , Italy.)
Abstract	The aim of this study was to validate the efficacy of a protocol for the management of infants born to colonised mothers with Group B Streptococcus (GBS). We studied a cohort of newborns admitted at the A. Gemelli University Hospital between May 2006 and December 2009. A total of 1,108 were newborns of mothers with GBS; 178 were children of mothers with unknown GBS status. Newborns were managed according to the care protocol in use at our division. Infected infants were born to mothers who underwent inadequate intrapartum antibiotic prophylaxis (IAP). No mother with complete IAP had an infected newborn. The incidence of invasive GBS infection in newborns of mothers with GBS was 0.4% and in newborns of mothers with unknown GBS status was 2.2%. Only 17.4% of newborns of mothers with GBS had risk factors. The complete IAP should always be performed regardless of the presence or the absence of risk factors. The care protocol applied offers successful management of the newborns of mothers with GBS, based on the correct execution of IAP, considering as a primary risk factor, the gestational age of < 35 weeks.
File Format	HTM / HTML
ISSN	01443615
Issue Number	8
Volume Number	34
e-ISSN	13646893
Journal	Journal of Obstetrics and Gynaecology
Language	English
Publisher	Taylor & Francis
Publisher Date	2014-11-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Streptococcus Agalactiae Prospective Studies Congenital Prevention & Control Humans Discipline Obstetrics Antibiotic Prophylaxis Epidemiology Journal Article Pregnancy Algorithms Infant, Premature Streptococcal Infections Validation Studies Female Italy Statistics & Numerical Data Diagnosis Discipline Gynaecology Infant, Newborn Observational Study
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology

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