NDLI: Piracy on the molecular level: human herpesviruses manipulate cellular chemotaxis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Cornaby, Caleb Tanner, Anne Stutz, Eric W. Poole, Brian D. Berges, Bradford K.
Description	Country affiliation: United States Author Affiliation: Cornaby C ( Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.); Tanner A ( Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.); Stutz EW ( Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.); Poole BD ( Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.); Berges BK ( Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.)
Abstract	Cellular chemotaxis is important to tissue homeostasis and proper development. Human herpesvirus species influence cellular chemotaxis by regulating cellular chemokines and chemokine receptors. Herpesviruses also express various viral chemokines and chemokine receptors during infection. These changes to chemokine concentrations and receptor availability assist in the pathogenesis of herpesviruses and contribute to a variety of diseases and malignancies. By interfering with the positioning of host cells during herpesvirus infection, viral spread is assisted, latency can be established and the immune system is prevented from eradicating viral infection.
File Format	HTM / HTML
ISSN	00221317
Issue Number	3
Volume Number	97
e-ISSN	14652099
Journal	Journal of General Virology
Language	English
Publisher	Microbiology Society
Publisher Date	2016-03-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline Virology Herpesviridae Humans Review Chemotaxis Journal Article Physiopathology Herpesviridae Infections Animals Immunology Genetics Physiology Receptors, Chemokine Chemokines
Content Type	Text
Resource Type	Article
Subject	Virology

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