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Pregnancy and perinatal outcome in women with hyperthyroidism.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Pillar, Nir Levy, Amalia Holcberg, Gershon Sheiner, Eyal
Spatial Coverage	Israel
Description	Country affiliation: Israel Author Affiliation: Pillar N ( Faculty of Health Sciences, Ben Gurion University of the Negev, Be'er-Sheva, Israel.)
Abstract	OBJECTIVE: To investigate pregnancy outcome for patients with treated hyperthyroidism. METHODS: A population-based study was performed comparing all singleton pregnancies of women with and women without hyperthyroidism at the Soroka University Medical Center, Be'er-Sheva, Israel, between January 1988 and January 2007. Stratified analysis, using a multiple logistic regression model, was performed to control for confounders. RESULTS: During the study period, there were 185636 singleton deliveries in the medical center. Of these, 189 (0.1%) were from women with hyperthyroidism. Using multivariate analysis with backward elimination, the following risk factors were significantly associated with hyperthyroidism: placental abruption; cesarean delivery; and advanced maternal age. No significant differences regarding perinatal outcome were noted between the groups. Women with hyperthyroidism had significantly higher rates of cesarean delivery than did women without hyperthyroidism (20.1% vs 13.1%; P<0.004), even after controlling for confounders. CONCLUSIONS: Treated hyperthyroidism was not associated with adverse perinatal outcome. However, hyperthyroidism was found to be an independent risk factor for cesarean delivery.
File Format	HTM / HTML
ISSN	00207292
Issue Number	1
Volume Number	108
e-ISSN	18793479
Journal	International Journal of Gynecology & Obstetrics
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2010-01-01
Publisher Place	Ireland
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Therapy Multivariate Analysis Age Factors Pregnancy Complications Humans Discipline Obstetrics Journal Article Young Adult Etiology Adult Female Retrospective Studies Complications Abruptio Placentae Hyperthyroidism Risk Factors Logistic Models Academic Medical Centers Physiopathology Pregnancy Cesarean Section Adolescent Discipline Gynecology Israel Pregnancy Outcome
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology

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