NDLI: Mortality and its predominant causes in a large cohort of patients with biopsy-determined inflammatory myositis.

Please wait, while we are loading the content...

Governance approval for multisite, non-interventional research: what can Harmonisation of Multi-Centre Ethical Review learn from the New South Wales experience?

Assessment of chronic hepatitis B: the importance of hepatitis B virus DNA testing.

Smoking cessation post-discharge following nicotine replacement therapy use during an inpatient admission.

Clinically important detection of infection as an 'incidental' finding during cancer staging using FDG-PET/CT.

Simple clinical score is associated with mortality and length of stay of acute general medical admissions to an Australian hospital.

Prevalence of paraproteinaemia in older Australians.

Indigenous beliefs about biomedical and bush medicine treatment efficacy for indigenous cancer patients: a review of the literature.

Early implementation of antifungal therapy in the management of febrile neutropenia is associated with favourable outcome during induction chemotherapy for acute leukaemias.

Hypothesis. The importance of a histological diagnosis when diagnosing and treating advanced cancer. Famous patient recovery may not have been from metastatic disease.

Dabigatran product familiarisation programmes: who benefits, who shouldn't get it?

Advances in gastrointestinal endoscopy.

Recreational drug use in type 1 diabetes: an invisible accomplice to poor glycaemic control?

New HIV diagnosis after occupational exposure screening: the importance of reporting needlestick injuries.

Lymphoma, thymoma and the wooden man: stiff-person syndrome post-thymoma excision and non-Hodgkin lymphoma remission.

Polypharmacy--we make it worse! A cross-sectional study from an acute admissions unit.

Trapped lung.

A fluffy chest radiograph.

Silver linings: a case study.

Multimodal treatment of post-tissue plasminogen activator-related intracerebral haemorrhage.

Mental health history and disruptive behaviours in the medical setting.

Fertility is significantly reduced by female genital tuberculosis: a case series.

Coronary CT angiography for patients with stable chest pain in the emergency department; an appraisal of current and emerging evidence.

Prehospital oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease.

Prehospital oxygen therapy in exacerbations of chronic obstructive pulmonary disease: the practical issues.

Treatment of refractory neurosarcoidosis with TNF-inhibitors: what lies ahead?

Year: 2012 Volume: 42 Issue: Supplementary 2

Year: 2012 Volume: 42 Issue: 1

Year: 2012 Volume: 42 Issue: Supplementary 1

Year: 2011 Volume: 41

Year: 2010 Volume: 40

Year: 2009 Volume: 39

Year: 2008 Volume: 38

Year: 2007 Volume: 37

Year: 2006 Volume: 36

Mortality and its predominant causes in a large cohort of patients with biopsy-determined inflammatory myositis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Limaye, V. Hakendorf, P. Woodman, R. J. Blumbergs, P. Roberts-Thomson, P.
Spatial Coverage	South Australia
Description	Country affiliation: Australia Author Affiliation: Limaye V ( Department of Rheumatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia. vidya.limaye@health.sa.gov.au)
Abstract	BACKGROUND: There is a paucity of literature on the patterns and predictors of mortality in idiopathic inflammatory myopathies (IIM). AIMS: To determine the patterns and predictors of mortality in a South Australian cohort of patients with biopsy-proven IIM. METHODS: The living/deceased status (and for deceased patients the causes of death) of patients with histologically determined IIM was determined from the Births, Deaths and Marriages Registry. Standardised mortality ratios (SMR) were generated compared with the age/gender matched South Australian population. The effect of presence/absence of the components of the Bohan and Peter criteria on risk ratios (RR) for mortality was determined. The effect of comorbidities and autoantibodies on mortality was investigated. RESULTS: The SMR for mortality in IIM was 1.75 and was significantly increased in all disease subgroups, being highest in patients with dermatomyositis (2.40). Dominant causes of death were cardiovascular disease (31%), infections (22%) and malignancy (11%). Risk factors for death were age at time of biopsy (hazard ratio 1.05), ischaemic heart disease (RR 2.97, P < 0.0001), proximal weakness at diagnosis (RR 1.8, P= 0.03), definite diagnosis of IIM per the Bohan and Peter criteria (RR 2.14, P < 0.0001), and the absence of autoantibodies (RR 1.9, P < 0.001). CONCLUSIONS: Patients with IIM are at 75% increased risk for mortality, and cardiovascular diseases account for the commonest causes of death. This study suggests a thorough cardiovascular evaluation of these patients is indicated, and raises the possibility that targeted interventions such as the use of aspirin or statins may improve outcomes in IIM.
File Format	HTM / HTML
ISSN	14440903
Issue Number	2
Volume Number	42
e-ISSN	14455994
Journal	Internal Medicine Journal
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2012-02-01
Publisher Place	Australia
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Kaplan-meier Estimate Research Support, Non-u.s. Gov't Comparative Study Mortality Humans Discipline Internal Medicine Inflammation Epidemiology Journal Article South Australia Pathology Follow-up Studies Myositis Registries Retrospective Studies Diagnosis Cohort Studies
Content Type	Text
Resource Type	Article
Subject	Internal Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Kasai hepatoportoenterostomy in South Australia: a case for 'centralized decentralization'.

Long term survival after evidence based treatment of acute myocardial infarction and revascularisation: follow-up of population based Perth MONICA cohort, 1984-2005

Implantable cardioverter-defibrillators: a long-term view.

Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up.

Survival in scleroderma: results from the population-based South Australian Register.

Clinical heterogeneity and prognostic features of South Australian patients with anti-synthetase autoantibodies.

Myelodysplasia Cutis Versus Leukemia Cutis.

Variability in hemoglobin A1c predicts all-cause mortality in patients with type 2 diabetes.

Success of five stapes prostheses evaluated by Kaplan-Meier product-survival procedure.

Mortality and its predominant causes in a large cohort of patients with biopsy-determined inflammatory myositis.

Similar Documents

Kasai hepatoportoenterostomy in South Australia: a case for 'centralized decentralization'.

Long term survival after evidence based treatment of acute myocardial infarction and revascularisation: follow-up of population based Perth MONICA cohort, 1984-2005

Implantable cardioverter-defibrillators: a long-term view.

Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up.

Survival in scleroderma: results from the population-based South Australian Register.

Clinical heterogeneity and prognostic features of South Australian patients with anti-synthetase autoantibodies.

Myelodysplasia Cutis Versus Leukemia Cutis.

Variability in hemoglobin A1c predicts all-cause mortality in patients with type 2 diabetes.

Success of five stapes prostheses evaluated by Kaplan-Meier product-survival procedure.

Mortality and its predominant causes in a large cohort of patients with biopsy-determined inflammatory myositis.