NDLI: Neoadjuvant chemotherapy-specific and overall treatment outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement.

Please wait, while we are loading the content...

Year: 2017 Volume: 39

Year: 2016 Volume: 38

Year: 2015 Volume: 37

Year: 2014 Volume: 36

Year: 2013 Volume: 35

Year: 2012 Volume: 34

Year: 2011 Volume: 33

Year: 2010 Volume: 32

Year: 2009 Volume: 31

Year: 2008 Volume: 30

Year: 2008 Volume: 30 Issue: 12

Year: 2008 Volume: 30 Issue: 11

Year: 2008 Volume: 30 Issue: 10

Year: 2008 Volume: 30 Issue: 9

Year: 2008 Volume: 30 Issue: 8

Year: 2008 Volume: 30 Issue: 7

Year: 2008 Volume: 30 Issue: 6

Year: 2008 Volume: 30 Issue: 5

Functional analysis of swallowing outcomes after supracricoid partial laryngectomy.

Investigation of tracheoesophageal voice prosthesis leakage patterns: patient's self-report versus clinician's confirmation.

Neoadjuvant chemotherapy-specific and overall treatment outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement.

Evolution of a paradigm for free tissue transfer reconstruction of lateral temporal bone defects.

Trismus in patients with oropharyngeal cancer: relationship with dose in structures of mastication apparatus.

Association of tumor satellite distance with prognosis and contralateral neck recurrence of tongue squamous cell carcinoma.

Differential expression of MUC1 and carbohydrate antigens in primary and secondary head and neck squamous cell carcinoma.

Transoral laser surgery for supraglottic cancer.

Year: 2008 Volume: 30 Issue: 4

Year: 2008 Volume: 30 Issue: 3

Year: 2008 Volume: 30 Issue: 2

Year: 2006 Volume: 28

Year: 2005 Volume: 27

Neoadjuvant chemotherapy-specific and overall treatment outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	DeMartelaere, Sheri L. Roberts, Dianna Burgess, Michael A. Morrison, William H. Pisters, Peter W. T. Sturgis, Erich M. Ho, Viet Esmaeli, Bita
Description	Country affiliation: United States Author Affiliation: DeMartelaere SL ( Section of Ophthalmology, Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.)
Abstract	BACKGROUND: Recent isolated case reports have suggested a potential role for neoadjuvant chemotherapy in patients with angiosarcoma. The goal of this report was to investigate the overall treatment outcomes and the neoadjuvant chemotherapy-specific outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement. METHODS: Our tumor database was searched for patients with angiosarcoma and periorbital involvement seen at our institution between 1981 and 2005. RESULTS: Twenty-one patients were identified,15 of whom had neoadjuvant chemotherapy and 6 of whom had a traditional approach of surgery followed by adjuvant therapy. Fourteen of 15 patients who had neoadjuvant chemotherapy had complete clinical response. Neoadjuvant chemotherapy made definitive surgery unnecessary for 9 patients. The median disease-free interval for the neoadjuvant chemotherapy group was 11.8 months (mean, 38.1 months; range, 2.4-239.6 months). Nine of the 15 patients had recurrences. The time from end of treatment to recurrence ranged from 2.6 to 24.5 months (median, 12.7 months). Five of the 6 patients who had primary surgical resection followed by adjuvant radiotherapy and/or chemotherapy had a complete clinical response, and the median disease-free interval was 31.8 months (mean, 35.9 months; range, 2.7-85 months). Two later developed recurrences, one at 2.7 months and the other at 31.8 months after the end of treatment. CONCLUSION: On the basis of this series, the authors conclude that neoadjuvant chemotherapy for periorbital angiosarcoma is a potentially attractive option and in some patients may obviate the need for major surgery, thereby preserving the eye and/or ocular adnexal structures. Given the propensity for recurrence and poor survival, the authors strongly recommend that these patients receive multidisciplinary evaluation and treatment at a major cancer center.
File Format	HTM / HTML
ISSN	10433074
Issue Number	5
Volume Number	30
e-ISSN	10970347
Journal	Head & Neck
Language	English
Publisher	Wiley
Publisher Date	2008-05-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Therapy Mortality Humans Middle Aged Neoplasm Recurrence, Local Hemangiosarcoma Male Aged, 80 And Over Journal Article Disease-free Survival Eyelid Neoplasms Discipline General Surgery Skin Neoplasms Survival Analysis Neoadjuvant Therapy Adult Female Aged Retrospective Studies Chemotherapy, Adjuvant Facial Neoplasms Radiotherapy, Adjuvant
Content Type	Text
Resource Type	Article
Subject	Otorhinolaryngology

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in