NDLI: Kinetic study of the 2-methyl-3-methoxy-4-phenylbutanoic acid produced by oxidation of microcystin in aqueous solutions.

Please wait, while we are loading the content...

Chemical availability and sediment toxicity of pyrethroid insecticides to Hyalella azteca: application to field sediment with unexpectedly low toxicity.

Concentrations and patterns of perfluoroalkyl acids in Georgia, USA surface waters near and distant to a major use source.

Acute toxicity of thioarsenates to Vibrio fischeri.

Exposure and effects assessment of resident mink (Mustela vison) exposed to polychlorinated dibenzofurans and other dioxin-like compounds in the Tittabawassee River basin, Midland, Michigan, USA.

More than inorganic copper is bioavailable to aquatic mosses at environmentally relevant concentrations.

Differential metallothionein induction patterns in fed and starved carp (Cyprinus carpio) during waterborne copper exposure.

Butyltin accumulation in two marine bivalves along a pollution gradient.

Mercury correlations among six tissues for four waterbird species breeding in San Francisco Bay, California, USA.

Influence of lake characteristics on the biomagnification of persistent organic pollutants in lake trout food webs.

Occurrence and mass loadings of n-alkanes in riverine runoff of the Pearl River Delta, South China: global implications for levels and inputs.

Chemical amplification in an invaded food web: seasonality and ontogeny in a high-biomass, low-diversity ecosystem.

Toxicity of perfluorooctane sulfonic acid and perfluorooctanoic acid on freshwater macroinvertebrates (Daphnia magna and Moina macrocopa) and fish (Oryzias $latipes)^{†}$

Year: 2008 Volume: 27 Issue: 9

Year: 2008 Volume: 27 Issue: 8

Year: 2008 Volume: 27 Issue: 7

Year: 2008 Volume: 27 Issue: 6

Year: 2008 Volume: 27 Issue: 5

Year: 2008 Volume: 27 Issue: 4

Year: 2008 Volume: 27 Issue: 2

Year: 2007 Volume: 26

Year: 2006 Volume: 25

Year: 2004 Volume: 23

Kinetic study of the 2-methyl-3-methoxy-4-phenylbutanoic acid produced by oxidation of microcystin in aqueous solutions.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wu, Xingqiang Xiao, Bangding Gong, Yan Wang, Zhi Chen, Xiaoguo Li, Renhui
Description	Country affiliation: China Author Affiliation: Wu X ( Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, China.)
Abstract	Microcystins (MCs) are a family of related cyclic hepatotoxic heptapeptides, of which more than 70 types have been identified. The chemically unique nature of the C20 beta-amino acid, (2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid (Adda), portion of the MCs has been exploited to develop a strategy to analyze the entirety. Oxidation of MCs causes the cleavage of MC Adda to form 2-methyl-3-methoxy-4-phenylbutanoic acid (MMPB). In the present study, we investigated the kinetics of MMPB produced by oxidation of the most-often-studied MC variant, MC-LR (L = leucine, R = arginine), with permanganate-periodate. This investigation allowed insight regarding the influence of the reaction conditions (concentration of the reactants, temperature, and pH) on the conversion rate. The results indicated that the reaction was second order overall and first order with respect to both permanganate and MC-LR. The second-order rate constant ranged from 0.66 to 1.35 M/s at temperatures from 10 to 30 degrees C, and the activation energy was 24.44 kJ/mol. The rates of MMPB production can be accelerated through increasing reaction temperature and oxidant concentration, and sufficient periodate is necessary for the formation of MMPB. The initial reaction rate under alkaline and neutral conditions is higher than that under acidic conditions, but the former decreases faster than the latter except under weakly acidic conditions. These results provided new insight concerning selection of the permanganate-periodate concentration, pH, and temperature needed for the oxidation of MCs with a high and stable yield of MMPB.
File Format	HTM / HTML
ISSN	07307268
Issue Number	10
Volume Number	27
e-ISSN	15528618
Journal	Environmental Toxicology and Chemistry
Language	English
Publisher	Wiley
Publisher Date	2008-10-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Potassium Permanganate Water Research Support, Non-u.s. Gov't Periodic Acid Temperature Phenylbutyrates Discipline Environmental Health Discipline Toxicology Chromatography, High Pressure Liquid Metabolism Microcystis Spectrophotometry, Ultraviolet Journal Article Chemistry Solutions Oxidation-reduction Discipline Chemistry Hydrogen-ion Concentration Kinetics Microcystins
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Immediate and long-term impacts of potassium permanganate on photosynthetic activity, survival and microcystin-LR release risk of Microcystis aeruginosa.

Oxidative treatment of azo dyes in aqueous solution by potassium permanganate.

Kinetic and mechanistic study of microcystin-LR degradation by nitrous acid under ultraviolet irradiation.

Detection of total microcystin in fish tissues based on lemieux oxidation, and recovery of 2-methyl-3-methoxy-4-phenylbutanoic acid (MMPB) by solid-phase microextraction gas chromatography-mass spectrometry (SPME-GC/MS)

Kinetic study of the oxidation and nitration of catechols in the presence of nitrous acid ionization equilibria.

Kinetics of Oxidation of dl-Tartaric Acid by Potassium Permanganate in Aqueuos and Aqueous Micellar Media

Kinetic studies of endosulfan photochemical degradations by ultraviolet light irradiation in aqueous medium.

Kinetics of uncatalyzed and surfactant catalyzed oxidation of amino acids by potassium permanganate in acid medium

Permanganate Oxidation of α-Amino Acids: Kinetic Correlations for the Nonautocatalytic and Autocatalytic Reaction Pathways

Kinetic study of the 2-methyl-3-methoxy-4-phenylbutanoic acid produced by oxidation of microcystin in aqueous solutions.

Similar Documents

Immediate and long-term impacts of potassium permanganate on photosynthetic activity, survival and microcystin-LR release risk of Microcystis aeruginosa.

Oxidative treatment of azo dyes in aqueous solution by potassium permanganate.

Kinetic and mechanistic study of microcystin-LR degradation by nitrous acid under ultraviolet irradiation.

Detection of total microcystin in fish tissues based on lemieux oxidation, and recovery of 2-methyl-3-methoxy-4-phenylbutanoic acid (MMPB) by solid-phase microextraction gas chromatography-mass spectrometry (SPME-GC/MS)

Kinetic study of the oxidation and nitration of catechols in the presence of nitrous acid ionization equilibria.

Kinetics of Oxidation of dl-Tartaric Acid by Potassium Permanganate in Aqueuos and Aqueous Micellar Media

Kinetic studies of endosulfan photochemical degradations by ultraviolet light irradiation in aqueous medium.

Kinetics of uncatalyzed and surfactant catalyzed oxidation of amino acids by potassium permanganate in acid medium

Permanganate Oxidation of α-Amino Acids: Kinetic Correlations for the Nonautocatalytic and Autocatalytic Reaction Pathways

Kinetic study of the 2-methyl-3-methoxy-4-phenylbutanoic acid produced by oxidation of microcystin in aqueous solutions.