NDLI: The relationship between total cholinesterase activity and mortality in four butterfly species.

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The relationship between total cholinesterase activity and mortality in four butterfly species.

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The relationship between total cholinesterase activity and mortality in four butterfly species.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bargar, Timothy A.
Description	Country affiliation: United States Author Affiliation: Bargar TA ( Southeast Ecological Science Center, US Geological Survey, Gainesville, Florida, USA. tbargar@usgs.gov)
Abstract	The relationship between total cholinesterase activity (TChE) and mortality in four butterfly species (great southern white [Ascia monuste], common buckeye [Junonia coenia], painted lady [Vanessa cardui], and julia butterflies [Dryas julia]) was investigated. Acute contact toxicity studies were conducted to evaluate the response (median lethal dose [LD50] and TChE) of the four species following exposure to the organophosphate insecticide naled. The LD50 for these butterflies ranged from 2.3 to 7.6 µg/g. The average level of TChE inhibition associated with significant mortality ranged from 26 to 67%, depending on the species. The lower bounds of normal TChE activity (2 standard deviations less than the average TChE for reference butterflies) ranged from 8.4 to 12.3 µM/min/g. As a percentage of the average reference TChE activity for the respective species, the lower bounds were similar to the inhibition levels associated with significant mortality, indicating there was little difference between the dose resulting in significant TChE inhibition and that resulting in mortality.
File Format	HTM / HTML
ISSN	07307268
Issue Number	9
Volume Number	31
e-ISSN	15528618
Journal	Environmental Toxicology and Chemistry
Language	English
Publisher	Wiley
Publisher Date	2012-09-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Naled Research Support, Non-u.s. Gov't Cholinesterase Inhibitors Species Specificity Toxicity Discipline Environmental Health Cholinesterases Discipline Toxicology Insecticides Lethal Dose 50 Metabolism Drug Effects Butterflies Journal Article Animals Discipline Chemistry Physiology
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis

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