NDLI: Analysis and dissipation of the antiparasitic agent ivermectin in cattle dung under different field conditions.

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Analysis and dissipation of the antiparasitic agent ivermectin in cattle dung under different field conditions.

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Analysis and dissipation of the antiparasitic agent ivermectin in cattle dung under different field conditions.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wohde, Manuel Blanckenhorn, Wolf U. Floate, Kevin D. Lahr, Joost Lumaret, Jean-Pierre Römbke, Jörg Scheffczyk, Adam Tixier, Thomas Düring, Rolf-Alexander
Description	Country affiliation: Germany Author Affiliation: Wohde M ( Institute of Soil Science and Soil Conservation, Justus Liebig University, Giessen, Germany.); Blanckenhorn WU ( Evolutionary Biology & Environmental Studies, University of Zurich, Zurich, Switzerland.); Floate KD ( Agriculture and Agri-Food Canada, Lethbridge, Alberta, Canada.); Lahr J ( Alterra, Wageningen University and Research Centre, Wageningen, The Netherlands.); Lumaret JP ( Centre for Evolutionary & Functional Ecology, Université Paul-Valéry, Montpellier, France.); Römbke J ( ECT Oekotoxikologie, Flörsheim, Germany.); Scheffczyk A ( ECT Oekotoxikologie, Flörsheim, Germany.); Tixier T ( Centre for Evolutionary & Functional Ecology, Université Paul-Valéry, Montpellier, France.); Düring RA ( Institute of Soil Science and Soil Conservation, Justus Liebig University, Giessen, Germany.)
Abstract	Cattle treated with the veterinary parasiticide ivermectin fecally excrete residues. The authors report the exposition and dissipation characteristics of these residues in dung of ivermectin-treated cattle and in soil beneath this dung on pastures in Canada, France, Switzerland, and The Netherlands. Residues were quantified for dung collected from cattle after 3 d, 7 d, 14 d, and 28 d posttreatment and subsequently exposed in the field for up to 13 mo. The authors optimized a high-performance liquid chromatography-fluorescence detection method to detect ivermectin residues in dung and soil matrices. They showed that a solid phase extraction and purification step generally can be eliminated to reduce the time and cost of these analyses. They also found that the addition of water to relatively dry samples improves the extraction efficiency of residues. They then analyzed the field samples to document differences in ivermectin dissipation in cattle dung among sites, with 50% dissipation times of up to 32 d and 90% dissipation times >396 d. They further showed that the dissipation characteristics of residues are comparable between dung of ivermectin-treated cattle and dung to which ivermectin has been added directly. Lastly, they report the first use of a desorption electrospray ionization-high-resolution-mass spectrometric method to detect residues of metabolites in a dung matrix. Environ Toxicol Chem 2016;35:1924-1933. © 2016 SETAC.
File Format	HTM / HTML
ISSN	07307268
Issue Number	8
Journal	Environmental Toxicology and Chemistry
Volume Number	35
e-ISSN	15528618
Language	English
Publisher	Wiley
Publisher Date	2016-08-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Environmental Health Discipline Toxicology Discipline Chemistry
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis

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