NDLI: Left ventricular mass and hypertrophy by echocardiography and cardiac magnetic resonance: the multi-ethnic study of atherosclerosis.

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Left ventricular mass and hypertrophy by echocardiography and cardiac magnetic resonance: the multi-ethnic study of atherosclerosis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Armstrong, Anderson C. Gjesdal, Ola Almeida, André Nacif, Marcelo Wu, Colin Bluemke, David A. Brumback, Lyndia Lima, João A. C.
Spatial Coverage	Baltimore
Description	Country affiliation: Brazil Author Affiliation: Armstrong AC ( Division of Cardiology, Johns Hopkins University, Baltimore, Maryland)
Abstract	BACKGROUND: Left ventricular mass (LVM) and hypertrophy (LVH) are important parameters, but their use is surrounded by controversies. We compare LVM by echocardiography and cardiac magnetic resonance (CMR), investigating reproducibility aspects and the effect of echocardiography image quality. We also compare indexing methods within and between imaging modalities for classification of LVH and cardiovascular risk. METHODS: Multi-Ethnic Study of Atherosclerosis enrolled 880 participants in Baltimore city, 146 had echocardiograms and CMR on the same day. LVM was then assessed using standard techniques. Echocardiography image quality was rated (good/limited) according to the parasternal view. LVH was defined after indexing LVM to body surface area, height(1.7) , height(2.7) , or by the predicted LVM from a reference group. Participants were classified for cardiovascular risk according to Framingham score. Pearson's correlation, Bland-Altman plots, percent agreement, and kappa coefficient assessed agreement within and between modalities. RESULTS: Left ventricular mass by echocardiography (140 ± 40 g) and by CMR were correlated (r = 0.8, P < 0.001) regardless of the echocardiography image quality. The reproducibility profile had strong correlations and agreement for both modalities. Image quality groups had similar characteristics; those with good images compared to CMR slightly superiorly. The prevalence of LVH tended to be higher with higher cardiovascular risk. The agreement for LVH between imaging modalities ranged from 77% to 98% and the kappa coefficient from 0.10 to 0.76. CONCLUSIONS: Echocardiography has a reliable performance for LVM assessment and classification of LVH, with limited influence of image quality. Echocardiography and CMR differ in the assessment of LVH, and additional differences rise from the indexing methods.
File Format	HTM / HTML
ISSN	07422822
e-ISSN	15408175
DOI	10.1111/echo.12303
Journal	Echocardiography
Issue Number	1
Volume Number	31
Language	English
Publisher	Wiley
Publisher Date	2014-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Echocardiography Comparative Study Sensitivity And Specificity Risk Factors Organ Size Ethnology Magnetic Resonance Imaging, Cine Heart Ventricles Reproducibility Of Results Pathology Baltimore Discipline Cardiology Hypertrophy, Left Ventricular Statistics & Numerical Data Diagnosis
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Cardiology and Cardiovascular Medicine

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