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Primary cardiac lymphoma presenting as an atypical type of hypertrophic cardiomyopathy.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kim, Dong-Hyeok Kim, Yong-Hyun Song, Woo-Hyuk Ahn, Jeong-Cheon
Description	Author Affiliation: Kim DH ( Division of Cardiology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea.)
Abstract	Primary cardiac lymphoma (PCL) is a very rare malignancy although cardiac involvement with the disseminated disease is not uncommon. We present a case of a 43-year-old man with PCL that initially presented as marked thickening of all cardiac walls and was mistakenly diagnosed as an atypical type of hypertrophic cardiomyopathy. The diagnosis of PCL was made with a delay of 9 months after the initial presentation, when atypical lymphocytes staining positive for CD79a and CD20 were demonstrated in the rapidly growing mediastinal and neck mass. Anthracycline-based chemotherapy and anti-CD20 immunotherapy resulted in a remarkable reduction in cardiac wall thickness and mediastinal mass. The first lesson to be learnt from this case is that PCL can present as a diffuse infiltrative disease without a mass. The second lesson is that prompt exploratory thoracotomy should not be delayed when the diagnosis is elusive.
File Format	HTM / HTML
ISSN	07422822
Issue Number	4
Volume Number	31
e-ISSN	15408175
Journal	Echocardiography
Language	English
Publisher	Wiley
Publisher Date	2014-04-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Lymphoma, Large B-cell, Diffuse Immunohistochemistry Humans Male Journal Article Case Reports Cardiomyopathy, Hypertrophic Dyspnea Etiology Discipline Cardiology Adult Diagnosis Heart Neoplasms Radiographic Image Enhancement Diagnosis, Differential Emergency Service, Hospital Echocardiography Risk Assessment Tomography, X-ray Computed Drug Therapy Antineoplastic Combined Chemotherapy Protocols Treatment Outcome Rare Diseases Delayed Diagnosis Therapeutic Use Biopsy, Needle Methods
Content Type	Text
Resource Type	Case study Article
Subject	Radiology, Nuclear Medicine and Imaging Cardiology and Cardiovascular Medicine

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