NDLI: Infection control and prevention practices implemented to reduce transmission risk of Middle East respiratory syndrome-coronavirus in a tertiary care institution in Saudi Arabia.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Butt, Taimur S. Koutlakis-Barron, Irene AlJumaah, Suliman AlThawadi, Sahar AlMofada, Saleh
Description	Author Affiliation: Butt TS ( Department of Emergency Medicine, King Faisal Specialist Hospital and Research Centre, Saudi Arabia. Electronic address: tbutt@kfshrc.edu.sa.); Koutlakis-Barron I ( Infection Control and Hospital Epidemiology, King Faisal Specialist Hospital and Research Centre, Saudi Arabia.); AlJumaah S ( Infection Control and Hospital Epidemiology, King Faisal Specialist Hospital and Research Centre, Saudi Arabia.); AlThawadi S ( Section of Microbiology, Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Saudi Arabia.); AlMofada S ( Department of Pediatrics, King Faisal Specialist Hospital and Research Centre, Saudi Arabia.)
Abstract	BACKGROUND: Transmission of Middle East respiratory syndrome-coronavirus (MERS-CoV) among health care workers (HCWs) and patients has been documented with mortality rate approximating 36%. We propose advanced infection control measures (A-IC) used in conjunction with basic infection control measures (B-IC) help reduce pathogen transmission. B-IC include standard and transmission-based precautions. A-IC are initiatives implemented within our center to enhance effectiveness of B-IC. OBJECTIVE: Study effectiveness of combining B-IC and A-IC to prevent transmission of MERS-CoV to HCWs. METHODS: A retrospective observational study was undertaken. A-IC measures include administrative support with daily rounds; infection control risk assessment; timely screening, isolation, and specimen analysis; collaboration; epidemic planning; stockpiling; implementation of contingency plans; full personal protective equipment use for advanced airway management; use of a real-time electronic isolation flagging system; infection prevention and control team on-call protocols; pretransfer MERS-CoV testing; and education. RESULTS: A total of 874 real-time polymerase chain reaction MERS-CoV tests were performed during the period beginning July 1, 2013, and ending January 31, 2015. Six hundred ninety-four non-HCWs were tested, of these 16 tested positive for MERS-CoV and their infection was community acquired. Sixty-nine percent of the confirmed MERS-CoV-positive cases were men, with an average age of 56 years (range, 19-84 years). Of the total tested for MERS-CoV, 180 individuals were HCWs with zero positivity. CONCLUSIONS: Adhering to a combination of B-IC and A-IC reduces the risk of MERS-CoV transmission to HCWs.
File Format	HTM / HTML
ISSN	01966553
Issue Number	5
Journal	American Journal of Infection Control
Volume Number	44
e-ISSN	15273296
Language	English
Publisher	Elsevier
Publisher Date	2016-05-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Communicable Diseases
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Public Health, Environmental and Occupational Health Epidemiology Health Policy

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