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Association between epilepsy and erectile dysfunction: evidence from a population-based study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Keller, Joseph Chen, Yi-Kuang Lin, Herng-Ching
Spatial Coverage	Taiwan
Description	Country affiliation: Taiwan Author Affiliation: Keller J ( Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.)
Abstract	INTRODUCTION: Although the association between epilepsy and sexual disorders has long been known, very few studies have attempted to explore the association between epilepsy and erectile dysfunction (ED). AIM: This population-based case-control study aimed to investigate the association between ED and a prior diagnosis with epilepsy. METHODS: This study used data from the Longitudinal Health Insurance Database 2000 in Taiwan. The cases comprised 6,427 patients with a diagnosis of ED and 32,135 controls who were frequency matched with cases based on 10-year age groups and index year. Conditional logistic regression was used to calculate the odds ratios (ORs) for prior epilepsy. MAIN OUTCOME MEASURE: The prevalence and risk of epilepsy between cases and controls. RESULTS: Of the sampled patients, 3,861 (14%) were diagnosed before the index date: 1,358 individuals (19.7%) were cases and 2,503 (12.1%) were controls. After adjusting for hypertension, diabetes, hyperlipidemia, renal disease, coronary heart disease, obesity, alcohol abuse/alcohol dependence syndrome, and socioeconomic status, conditional logistic regression analysis revealed that patients with ED were more likely to have been diagnosed with prior epilepsy than controls (OR = 1.83, 95% CI = 1.51-2.21). Compared with controls, the adjusted ORs for prior generalized epilepsy and partial epilepsy for cases were 2.13 (95% CI = 1.52-3.00) and 1.64 (95% CI = 1.31-2.06), respectively. The most pronounced associations were detected in ED cases aged between 30 and 39 who were 3.04 (95% CI = 1.67-5.50) times more likely than controls to have been previously diagnosed with epilepsy. CONCLUSIONS: Our findings suggest a positive correlation between ED and a prior diagnosis with epilepsy.
File Format	HTM / HTML
ISSN	17436095
Issue Number	9
Volume Number	9
e-ISSN	17436109
Journal	The Journal of Sexual Medicine
Language	English
Publisher	Elsevier
Publisher Date	2012-09-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Urology Discipline Sexology Epilepsy Epidemiology Erectile Dysfunction Adolescent Adult Age Distribution Aged Case-control Studies Databases, Factual Humans Logistic Models Male Middle Aged Odds Ratio Prevalence Taiwan Young Adult Journal Article
Content Type	Text
Resource Type	Article
Subject	Endocrinology, Diabetes and Metabolism Urology Endocrinology Reproductive Medicine Psychiatry and Mental Health Obstetrics and Gynecology

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