NDLI: The impact of continued intervention on weight: Five-year results from the weight loss maintenance trial.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Coughlin, Janelle W. Brantley, Phillip J. Champagne, Catherine M. Vollmer, William M. Stevens, Victor J. Funk, Kristine Dalcin, Arlene T. Jerome, Gerald J. Myers, Valerie H. Tyson, Crystal Batch, Bryan C. Charleston, Jeanne Loria, Catherine M. Bauck, Alan Hollis, Jack F. Svetkey, Laura P. Appel, Lawrence J.
Description	Country affiliation: United States Author Affiliation: Coughlin JW ( Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.); Brantley PJ ( Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA.); Champagne CM ( Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, USA.); Vollmer WM ( Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, USA.); Stevens VJ ( The Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.); Funk K ( The Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.); Dalcin AT ( The Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.); Jerome GJ ( Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA.); Myers VH ( Division of General Internal Medicine, Johns Hopkins University, Baltimore, Maryland, USA.); Tyson C ( Department of Kinesiology, Towson University, Towson, Maryland, USA.); Batch BC ( Klein Buendel, Inc, Golden, Colorado, USA.); Charleston J ( Division of Nephrology/Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.); Loria CM ( Duke Hypertension Center and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA.); Bauck A ( Duke Hypertension Center and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA.); Hollis JF ( Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA.); Svetkey LP ( National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.); Appel LJ ( The Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.)
Abstract	OBJECTIVE: In the Weight Loss Maintenance (WLM) Trial, a personal contact (PC) intervention sustained greater weight loss relative to a self-directed (SD) group over 30 months. This study investigated the effects of continued intervention over an additional 30 months and overall weight change across the entire WLM Trial. METHODS: WLM had 3 phases. Phase 1 was a 6-month weight loss program. In Phase 2, those who lost ≥4 kg were randomized to a 30-month maintenance trial. In Phase 3, PC participants (n = 196, three sites) were re-randomized to no further intervention (PC-Control) or continued intervention (PC-Active) for 30 more months; 218 SD participants were also followed. RESULTS: During Phase 3, weight increased 1.0 kg in PC-Active and 0.5 kg in PC-Control (mean difference 0.6 kg; 95% CI:-1.4 to 2.7; P = 0.54). Mean weight change over the entire study was -3.2 kg in those originally assigned to PC (PC-Combined) and -1.6 kg in SD (mean difference -1.6 kg; 95% CI:-3.0 to -0.1; P = 0.04). CONCLUSIONS: After 30 months of the PC maintenance intervention, continuation for another 30 months provided no additional benefit. However, across the entire study, weight loss was slightly greater in those originally assigned to PC.
File Format	HTM / HTML
ISSN	19307381
Issue Number	5
Journal	Obesity
Volume Number	24
e-ISSN	1930739X
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2016-05-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Endocrinology

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