NDLI: Preliminary comparison of radiolucent cages containing either autogenous cancellous bone or hydroxyapatite graft in multilevel cervical fusion.

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Preliminary comparison of radiolucent cages containing either autogenous cancellous bone or hydroxyapatite graft in multilevel cervical fusion.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Chang, Wei-Chieh Tsou, Hsi-Kai Chen, Wen-Shian Chen, Chi-Chang Shen, Chiung-Chyi
Description	Author Affiliation: Chang WC ( Department of Neurosurgery, Taichung Veterans General Hospital, 160 Taichung-Kong Road, Sec. 3, Taichung, Taiwan 407. changweichieh@yahoo.com.tw)
Abstract	We compared the preliminary outcomes of cervical fusion performed using radiolucent cages containing either cancellous bone or hydroxyapatite graft. From July 2004 to June 2006, 45 consecutive patients presented with a total of 109 levels of degenerative disc disease between the C2 and C7 levels. Each patient underwent anterior cervical discectomy and fusion (ACDF) for each affected cervical disc. The retrospective analysis of the cage fillers was divided into group 1 (23 patients with 56 affected cervical levels) who received cages packed with cancellous bone marrow, and group 2 (22 patients with 53 affected cervical levels) who received cages packed with hydroxyapatite graft. Bone marrow was harvested from the anterior iliac crest. The Prolo scale was used to assess both the economic and functional status postoperatively. The Yates' correction to test independence in a contingency was used to compare the fusion rate of both groups post-operatively at day 1 and at 1, 3 and 6 month follow-up. At a mean follow-up of 12 months, the fusion rates observed in groups 1 and 2, respectively, were 21.4% and 13.2% after 1 month, 76.8% and 64.2% after 3 months, and 98.2% and 96.2% after 6 months. Functional and economic status were better in group 2, with a statistical significance (p<0.05) observed at the 3-month follow-up. Although hydroxyapatite graft is an osteoconductive, rather than osteoinductive, material, when used as a cage filler it is a safe and efficient substitute for cancellous bone.
File Format	HTM / HTML
ISSN	09675868
Issue Number	6
Volume Number	16
e-ISSN	15322653
Journal	Journal of Clinical Neuroscience
Language	English
Publisher	Elsevier
Publisher Date	2009-06-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Medicine Bone Transplantation Methods Durapatite Therapeutic Use Internal Fixators Statistics & Numerical Data Intervertebral Disc Displacement Surgery Spinal Fusion Spondylosis Adult Aged Arthroplasty, Replacement Instrumentation Bone Substitutes Cervical Vertebrae Pathology Diskectomy Female Humans Ilium Transplantation Male Middle Aged Prosthesis Design Prosthesis Implantation Radiography Recovery Of Function Retrospective Studies Transplantation, Autologous Treatment Outcome Comparative Study Journal Article
Content Type	Text
Resource Type	Article
Subject	Neurology Physiology (medical) Neurology (clinical) Surgery

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