NDLI: Melkersson-Rosenthal syndrome: a review of seven patients.

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Melkersson-Rosenthal syndrome: a review of seven patients.

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Melkersson-Rosenthal syndrome: a review of seven patients.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Liu, Ruozhuo Yu, Shengyuan
Description	Country affiliation: China Author Affiliation: Liu R ( Department of Neurology, Chinese PLA General Hospital, No. 28, Fuxing Road, Beijing 100853, China.)
Abstract	Melkersson-Rosenthal syndrome (MRS) is a rare disorder consisting of a triad of persistent or recurrent orofacial edema, relapsing facial paralysis and fissured tongue. It is difficult to diagnose and treat. A retrospective review of our MRS patients was performed. The medical files, and treatment, radiologic and histopathologic records of these patients were reviewed. The study group consisted of seven male MRS patients. In four patients, the three classical manifestations were present simultaneously. Neuroimaging examinations found facial soft-tissue thickening and swelling in two patients. The indicators of the disease in our patients were as follows: two had family histories, two had elevated levels of protein in the cerebrospinal fluid, one had an increased immunoglobulin G level in the blood and one had reactive arthritis. All patients responded to systemic corticosteroid treatment. We discuss the genetic, infectious and immunologic factors in the etiology of MRS. Neuroimaging examinations were useful in determining the diagnosis and in determining whether the initial treatment of MRS should be with systemic corticosteroids.
File Format	HTM / HTML
ISSN	09675868
Issue Number	7
Volume Number	20
e-ISSN	15322653
Journal	Journal of Clinical Neuroscience
Language	English
Publisher	Elsevier
Publisher Date	2013-07-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Medicine Melkersson-rosenthal Syndrome Etiology Pathology Therapy Adolescent Adrenal Cortex Hormones Therapeutic Use Adult Humans Male Middle Aged Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Neurology Physiology (medical) Neurology (clinical) Surgery

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