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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Shingleton, Bradford J. Laul, Anupam Nagao, Karina Wolff, Brian O'Donoghue, Mark Eagan, Edward Flattem, Nancy Desai-Bartoli, Sonalee |
| Description | Country affiliation: United States Author Affiliation: Shingleton BJ ( Private Practice, Boston, Massachusetts, USA. bjshingleton@eyeboston.com) |
| Abstract | PURPOSE: To assess the effect of phacoemulsification with posterior chamber intraocular lens (IOL) implantation performed by a single surgeon on intraocular pressure (IOP) and glaucoma medication requirements in pseudoexfoliation (PFX) eyes with or without glaucoma. SETTING: Private practice, Boston, Massachusetts, USA. METHODS: This retrospective analysis comprised 1122 eyes with PFX having uneventful phacoemulsification with IOL implantation. Of the eyes, 882 did not have glaucoma (PFX group) and 240 had glaucoma (PXG group). A comparative outcomes analysis was performed; the analysis focused on IOP and change in glaucoma medication requirements between the 2 groups. RESULTS: The mean IOP was statistically significantly reduced through 7 years postoperatively compared with preoperatively in the PFX group. The PXG group had reduced mean IOP for 1 year and reduced glaucoma medication requirements at almost all postoperative time intervals. Higher mean preoperative IOP was associated with a greater reduction in mean IOP postoperatively in both groups. Intraocular pressure spikes (> 30 mm Hg) 1 day postoperatively occurred in 4% in the PFX group and 17% in the PXG group. Postoperatively, 2.7% of PFX eyes progressed to a need for glaucoma medication and 3.7% of PXG eyes progressed to a need for laser and/or glaucoma surgery. CONCLUSIONS: A long-term reduction in mean IOP occurred in PFX eyes with and without glaucoma. The IOP reduction was proportional to the preoperative IOP; higher preoperative IOP was associated with a greater reduction in IOP. Glaucoma progression in both groups was low, suggesting a protective effect of phacoemulsification on IOP in these eyes. |
| File Format | HTM / HTML |
| ISSN | 08863350 |
| Issue Number | 11 |
| Volume Number | 34 |
| e-ISSN | 18734502 |
| Journal | Journal of Cataract & Refractive Surgery |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2008-11-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Ophthalmology Exfoliation Syndrome Complications Glaucoma, Open-angle Prevention & Control Intraocular Pressure Lens Implantation, Intraocular Phacoemulsification Aged Disease Progression Female Etiology Physiopathology Humans Male Retrospective Studies Tonometry, Ocular Visual Acuity Comparative Study Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology Sensory Systems Surgery |
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