NDLI: Assessment of a new averaging algorithm to increase the sensitivity of axial eye length measurement with optical biometry in eyes with dense cataract.

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Assessment of a new averaging algorithm to increase the sensitivity of axial eye length measurement with optical biometry in eyes with dense cataract.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hirnschall, Nino Murphy, Sinead Pimenides, Dimitris Maurino, Vincenzo Findl, Oliver
Description	Country affiliation: United kingdom Author Affiliation: Hirnschall N ( Moorfields Eye Hospital NHS Trust, London, United Kingdom.)
Abstract	PURPOSE: To assess the capability of new software to decrease the proportion of eyes that have insufficient signal-to-noise ratio (SNR) in optical biometry. SETTING: Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. DESIGN: Evaluation of diagnostic test or technology. METHODS: In a prospective study, consecutive cataract patients coming for biometry who were unsuccessfully measured with the former software (version 4) of the IOLMaster partial coherence interferometry (PCI) device were reevaluated with the new composite software (version 5). Subsequently, in a retrospective study, consecutive cataract patients were measured with software version 5. For unsuccessful scans, the type and intensity of cataract were assessed at the slitlamp. RESULTS: Altogether, 2713 eyes (1956 patients) were included in the study. The prospective study comprised 458 eyes (244 patients), 10.6% of which could not be measured successfully with software version 4. With the composite software, 30% of cases were measured successfully, with a higher proportion (42%) in the posterior subcapsular cataract subgroup. In the retrospective study, of 2255 eyes (1712 patients), 4.7% were not measured successfully using the new algorithm because of white cataract (70 eyes), posterior subcapsular cataract (14 eyes), or dense nuclear cataract combined with posterior subcapsular cataract (13 eyes) or for other reasons (8 eyes). CONCLUSION: The composite software (version 5) enhanced the SNR, allowing valid measurements in eyes in which optical biometry had previously failed, especially in cases of posterior subcapsular cataract. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. Additional disclosure is found in the footnotes.
File Format	HTM / HTML
ISSN	08863350
Issue Number	1
Volume Number	37
e-ISSN	18734502
Journal	Journal of Cataract & Refractive Surgery
Language	English
Publisher	Elsevier
Publisher Date	2011-01-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ophthalmology Algorithms Axial Length, Eye Pathology Cataract Diagnosis Adult Aged Aged, 80 And Over Biometry Female Humans Male Middle Aged Prospective Studies Retrospective Studies Sensitivity And Specificity Young Adult Comparative Study Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Surgery

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