| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Muftuoglu, Orkun Ayar, Orhan Hurmeric, Volkan Orucoglu, Faik Kilic, Ilkay |
| Description |
Country affiliation: Turkey Author Affiliation: Muftuoglu O ( From the Department of Ophthalmology (Muftuoglu), Medipol University, Birinci Eye Hospital (Orucoglu), and Istanbul Egitim Arastirma Hastanesi (Kilic), Istanbul, the Department of Ophthalmology (Ayar), Zonguldak Bülent Ecevit University, Zonguldak, and Dunya Eye Hospital (Hurmeric), Ankara, Turkey.); Ayar O ( From the Department of Ophthalmology (Muftuoglu), Medipol University, Birinci Eye Hospital (Orucoglu), and Istanbul Egitim Arastirma Hastanesi (Kilic), Istanbul, the Department of Ophthalmology (Ayar), Zonguldak Bülent Ecevit University, Zonguldak, and Dunya Eye Hospital (Hurmeric), Ankara, Turkey.); Hurmeric V ( From the Department of Ophthalmology (Muftuoglu), Medipol University, Birinci Eye Hospital (Orucoglu), and Istanbul Egitim Arastirma Hastanesi (Kilic), Istanbul, the Department of Ophthalmology (Ayar), Zonguldak Bülent Ecevit University, Zonguldak, and Dunya Eye Hospital (Hurmeric), Ankara, Turkey.); Orucoglu F ( From the Department of Ophthalmology (Muftuoglu), Medipol University, Birinci Eye Hospital (Orucoglu), and Istanbul Egitim Arastirma Hastanesi (Kilic), Istanbul, the Department of Ophthalmology (Ayar), Zonguldak Bülent Ecevit University, Zonguldak, and Dunya Eye Hospital (Hurmeric), Ankara, Turkey.); Kilic I ( From the Department of Ophthalmology (Muftuoglu), Medipol University, Birinci Eye Hospital (Orucoglu), and Istanbul Egitim Arastirma Hastanesi (Kilic), Istanbul, the Department of Ophthalmology (Ayar), Zonguldak Bülent Ecevit University, Zonguldak, and Dunya Eye Hospital (Hurmeric), Ankara, Turkey.) |
| Abstract |
PURPOSE: To compare the multimetric D index and other keratoconus-screening parameters in patients with clinical keratoconus in 1 eye and subclinical keratoconus in the fellow eye. SETTING: Medipol University Hospital and Birinci Eye Hospital, Istanbul, Turkey. DESIGN: Retrospective case-control study. METHODS: Patients with clinical keratoconus in 1 eye and subclinical keratoconus in the fellow eye and eyes of normal subjects were evaluated with a rotating Scheimpflug imaging system (Pentacam). Parameters included anterior curve analysis, keratometry (K) values, minimum corneal thickness, pachymetric progression index, Ambrósio relational thickness, posterior elevation, back difference elevation, and D-index values. The receiver operating characteristic (ROC) curves were analyzed to evaluate the area under curve (AUC), sensitivity, and specificity of each parameter. RESULTS: Forty-five patients and 67 normal subjects were evaluated. The pachymetric progression indices, posterior elevation, and the D-index measurements were statistically significantly higher whereas corneal thickness and Ambrósio relational thickness measurements were significantly lower in eyes with keratoconus or subclinical keratoconus than in eyes of normal subjects (P < .05). Using the ROC analysis, the AUC values of the mean steep K, minimum corneal thickness, pachymetric progression index minimum, Ambrósio relational thickness maximum, posterior elevation, back difference elevation, and D index to distinguish between subclinical keratoconus from control subjects were 0.52, 0.64, 0.71, 0.72, 0.71, 0.76, and 0.83, respectively. CONCLUSION: The new multimetric D index seems to be better than other single-metric parameters in diagnosing keratoconus and subclinical keratoconus with good specificity. However, the sensitivity levels of all parameters were relatively limited in the diagnosis of subclinical keratoconus. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. |
| File Format |
HTM / HTML |
| ISSN |
08863350 |
| Issue Number |
3 |
| Volume Number |
41 |
| e-ISSN |
18734502 |
| Journal |
Journal of Cataract & Refractive Surgery |
| Language |
English |
| Publisher |
Elsevier |
| Publisher Date |
2015-03-01 |
| Publisher Place |
United States |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Discipline Ophthalmology Cornea Pathology Corneal Pachymetry Methods Corneal Topography Diagnostic Imaging Keratoconus Diagnosis Adolescent Adult Area Under Curve Case-control Studies Female Humans Physiopathology Male Middle Aged Roc Curve Refraction, Ocular Physiology Retrospective Studies Sensitivity And Specificity Young Adult Comparative Study Journal Article |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Ophthalmology Sensory Systems Surgery |
