NDLI: High accuracy of home-based community rapid HIV testing in rural Malawi.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Molesworth, Anna M. Ndhlovu, Richard Banda, Emmanuel Saul, Jacqueline Ngwira, Bagrey Glynn, Judith R. Crampin, Amelia C. French, Neil
Spatial Coverage	Malawi
Description	Country affiliation: Malawi Author Affiliation: Molesworth AM ( Karonga Prevention Study, Karonga District, Malawi.)
Abstract	OBJECTIVE: To assess the performance of rapid HIV antibody tests when used as part of a home-based community wide counseling and testing strategy in northern Malawi. DESIGN: A cross-sectional population survey of HIV infection, 2007 to 2008. METHODS: Adults aged 15 years or older in a demographic surveillance area were counseled and then offered an HIV test at their home by government-certified counselors. Two initial rapid tests (Determine and Uni-Gold) were performed on all samples and a third, tie-breaker test (SD Bioline) used to resolve discordant results. All people who wanted to know were posttest-counseled and informed of their results with referral to local clinical services if found to be HIV-positive. Laboratory quality control comprised retesting all positive and every tenth negative venous blood sample collected. RESULTS: A total of 10,819 adults provided venous blood samples for HIV testing, of whom 7.5% (813) were HIV-positive. The accuracy of the parallel testing strategy used was high with 99.6% sensitivity, 100.0% specificity, 99.9% positive predictive value, and 99.9% negative predictive value. CONCLUSION: Face-to-face rapid testing by health personnel with minimum training at the client's home performs well when used on a wide scale in the community setting.
File Format	HTM / HTML
ISSN	15254135
e-ISSN	10779450
DOI	10.1097/QAI.0b013e3181f98628
Journal	JAIDS Journal of Acquired Immune Deficiency Syndromes
Issue Number	5
Volume Number	55
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2010-12-15
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline AIDS Aids Serodiagnosis Hiv Infections Diagnosis Mass Screening Adolescent Cost-benefit Analysis Counseling Epidemiology Psychology Home Care Services Malawi Population Surveillance Rural Population Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Pharmacology (medical)

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