NDLI: F-FDG PET/CT and contrast-enhanced CT findings of pulmonary cryptococcosis.

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F-FDG PET/CT and contrast-enhanced CT findings of pulmonary cryptococcosis.

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F-FDG PET/CT and contrast-enhanced CT findings of pulmonary cryptococcosis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wang, Si-Yun Chen, Gang Luo, Dong-Lan Shao, Dan Liu, En-Tao Sun, Taotao Wang, Shu-Xia
Description	Author Affiliation: Wang SY ( Department of PET Center, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: wang_shuxia@outlook.com.); Chen G ( Department of Thoracic Surgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: cgggh@outlook.com.); Luo DL ( Department of Pathology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: 695532870@qq.com.); Shao D ( Department of PET Center, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: shaodan501@outlook.com.); Liu ET ( Department of PET Center, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: GDGH2015@gmail.com.); Sun T ( Department of PET Center, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: sunmoodsdaisy@bjmu.edu.cn.); Wang SX ( Department of PET Center, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China. Electronic address: wsyggh@outlook.com.)
Abstract	PURPOSE: Pulmonary cryptococcosis is an uncommon cause of pulmonary nodules in non-AIDS patients. This study reports the F-fluorodeoxyglucose-positron emission tomography ( F-FDG PET/CT) and contrast-enhanced CT (CE-CT) findings of 42 patients with pulmonary cryptococcosis. MATERIALS AND METHODS: A retrospective review of the F-FDG PET/CT and CE-CT findings of 42 patients with histologically proven pulmonary cryptococcosis was conducted. All patients underwent PET/CT and CE-CT in the same session. The CT diagnosis was based on the location, morphological features, and enhancement of lesions. The PET/CT findings were recorded, and clinical data and surgical and histopathological findings were collected. RESULTS: The results of the PET scans revealed that 37 (88%) of 42 patients showed higher FDG uptake, and 5 (12%) patients demonstrated lower FDG uptake than the mediastinal blood pool. The maximum standardized uptake value (SUV) of pulmonary cryptococcosis ranged from 1.4 to 13.0 (average: 5.7±3.3, median 4.9). A single nodular pattern was the most prevalent pattern observed and was found in 29 (69%) patients. This pattern was followed by scattered nodular (n=4, 10%), clustered nodular (n=3, 7%), mass-like (n=3, 7%), and bronchopneumonic (n=3, 7%) patterns. The most frequent pattern of immunocompetent patients was the single nodular pattern (29 of 33, 88%). Immunocompromised patients most frequently pattern exhibited mass-like (3 of 9, 33%) and bronchopneumonic (3 of 9, 33%) patterns. CONCLUSION: Pulmonary cryptococcosis most commonly appears as single nodules in immunocompetent patients. Mass-like and bronchopneumonic patterns were common in immunocompromised patients. In 88% of patients, lung lesions showed high FDG uptake, thus mimicking a possible malignant condition.
File Format	HTM / HTML
ISSN	0720048X
Journal	European Journal of Radiology
Volume Number	89
e-ISSN	18727727
Language	English
Publisher	Elsevier
Publisher Date	2017-04-01
Publisher Place	Ireland
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging

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