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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Fuzinatto, Cristiane F. Flohr, Letícia Melegari, Silvia P. Matias, William G. |
| Spatial Coverage | Brazil |
| Description | Country affiliation: Brazil Author Affiliation: Fuzinatto CF ( Laboratório de Toxicologia Ambiental, LABTOX, Departamento de Engenharia Sanitária e Ambiental, Universidade Federal de Santa Catarina, Campus Universitário, CEP: 88040-970, Florianópolis, SC, Brazil.) |
| Abstract | In an effort to characterize the pollution of surface waters by potentially genotoxic agents, this study aimed at assessing the frequency of micronucleated (MN) erythrocytes of the fish species, Oreochromis niloticus, from the Cubatão do Sul River. This river is the source of drinking water for the region of Florianópolis, capital of Santa Catarina State, Brazil. Negative control fish showed low frequency of MN, ranging between 0.49 and 0.90. Positive control (potassium dichromate 2.5 mg/L) organisms showed high MN frequency (16.82-17.25). The MN frequency increased along the river (Site 1--1.24 winter 2011; Site 4--9.76 summer 2011). Based on the observation of elevated MN erythrocytes frequency in O. niloticus exposed to water samples from along the river course, we conclude that the complex environmental mixtures of water from the Cubatão do Sul River have genotoxic potential. This genotoxicity most likely originated from agricultural runoff and domestic effluents released without treatment, based on the evidence from literature data and a survey in the region. This study provides a scientific basis for future studies regarding the genotoxicity of complex environmental mixtures in natural environments. |
| File Format | HTM / HTML |
| ISSN | 01476513 |
| Volume Number | 98 |
| e-ISSN | 10902414 |
| Journal | Ecotoxicology and Environmental Safety |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-12-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Sciences Cichlids Genetics Water Pollutants, Chemical Toxicity Animals Brazil Cell Nucleus Dna Damage Environmental Monitoring Erythrocytes Drug Effects Ultrastructure Micronucleus Tests Rivers Chemistry Isolation & Purification Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pollution Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health |
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