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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Döcker, D. Marx, U. Braun, B. |
| Description | Author Affiliation: Döcker D ( Medizinische Klinik I, Klinikum am Steinenberg, Kreiskliniken Reutlingen gGmbH, Reutlingen. braun_b@kreisklinikenreutlingen.de) |
| Abstract | HISTORY AND CLINICAL FINDINGS: A 56-year-old woman presented with pronounced petechia. She complained about recurrent fever and night sweat for two weeks, having felt unwell during the past years. INVESTIGATIONS: Laboratory examinations showed thrombocytopenia, leukopenia and considerably elevated liver enzymes. Antinuclear antibodies and antibodies against double-stranded DNA were positive. Sonography showed a slightly enlarged liver with multiple surrounding lymph nodes, splenomegaly and chronic-atrophic thyroiditis. Gastroscopy revealed several polypes which were immunohistochemically classified as neuroendocrine tumors (NET). DIAGNOSIS, TREATMENT AND COURSE: Systemic lupus erythematosus (SLE) with involvement of several organs was diagnosed and high doses of steroids were given. The steroid was then gradually reduced and changed to azathioprine. The NET were removed endoscopically. CONCLUSION: Neuroendocrine tumors are rare and localised to the stomach in only 2 - 4 %. Only three cases of gastric NET in the context of SLE with autoimmune gastritis have been reported so far in the literature. |
| File Format | HTM / HTML |
| ISSN | 00120472 |
| Issue Number | 36 |
| Volume Number | 135 |
| e-ISSN | 14394413 |
| Journal | DMW - Deutsche Medizinische Wochenschrift |
| Language | German |
| Publisher | Thieme Medical Publishers |
| Publisher Date | 2010-09-01 |
| Publisher Place | Germany |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline Medicine Lupus Erythematosus, Systemic Complications Neuroendocrine Tumors Stomach Neoplasms Antibodies, Antinuclear Analysis Azathioprine Therapeutic Use Dna Immunology Female Gastroscopy Humans Immunosuppressive Agents Diagnosis Drug Therapy Middle Aged Surgery Steroids Case Reports English Abstract Journal Article |
| Alternative Title | Gastric neuroendocrine tumors in a woman with systemic lupus erythematosus |
| Content Type | Text |
| Resource Type | Case study Article |
| Subject | Medicine |
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