NDLI: Angina pectoris ohne Koronarstenosen

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Yilmaz, A. Sechtem, U.
Description	Author Affiliation: Yilmaz A ( Abteilung für Kardiologie, Robert-Bosch-Krankenhaus Stuttgart.)
Abstract	This review aims at demonstrating current concepts for the occurrence of angina pectoris (AP) and myocardial ischemia in patients without significant epicardial stenoses based on typical clinical examples. For applying these concepts, it is of utmost importance to clinically distinguish patients with resting AP only from those with exercise-induced symptoms or both. Resting AP may not only be caused by plaque rupture and subsequent coronary thrombosis, but may also be due (especially when repeated attacks occur in the early morning hours) to coronary vasospasm (in the microvasculature as well as in epicardial coronary segments). Similarly, exercise-induced AP and/or a pathological exercise test result may not only be caused by severe coronary stenoses, but may also be due to a reduced coronary perfusion reserve secondary to microvascular dysfunction. Hence, a pathological non-invasive stress-test result should not be necessarily described as 'false positive' in case of the absence of any significant stenosis. In principle, proatherogenic cardiovascular risk factors are not only associated with atherosclerotic coronary artery disease (CAD), but also with the occurrence of a coronary vasomotility disorder. Both disease entities are characterised by the occurrence of myocardial ischemia. So far, the exact pathomechanism of respective subforms of coronary vasomotility disorders has not yet been not elucidated in detail. Endothelial dysfunction, abnormalities of the smooth muscle cells in the media as well as genetic predisposition or specific immunological abnormalities are discussed as underlying reasons. Intracoronary provocative testing (such as the acetylcholine-test) may help to diagnose as well as to differentiate the different subforms of coronary vasomotility disorders.
File Format	HTM / HTML
ISSN	00120472
Issue Number	39
Volume Number	135
e-ISSN	14394413
Journal	DMW - Deutsche Medizinische Wochenschrift
Language	German
Publisher	Thieme Medical Publishers
Publisher Date	2010-10-01
Publisher Place	Germany
Access Restriction	Subscribed
Subject Keyword	Discipline Medicine Coronary Stenosis Electrocardiography Exercise Test Microvascular Angina Diagnosis Etiology Acetylcholine Adult Angina Pectoris Coronary Angiography Coronary Thrombosis Diagnosis, Differential Diffusion Magnetic Resonance Imaging Female Humans Magnetic Resonance Angiography Male Middle Aged Myocarditis Parvoviridae Infections Parvovirus B19, Human Sensitivity And Specificity Vasodilator Agents Case Reports English Abstract Journal Article Review
Alternative Title	Angina pectoris without coronary stenosis--current concepts
Content Type	Text
Resource Type	Case study Article
Subject	Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in