NDLI: The effects of body mass index on changes in prostate-specific antigen levels and prostate volume over 15 years of follow-up: implications for prostate cancer detection.

Please wait, while we are loading the content...

The effects of body mass index on changes in prostate-specific antigen levels and prostate volume over 15 years of follow-up: implications for prostate cancer detection.

Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data.

Obesity and thyroid cancer risk among U.S. men and women: a pooled analysis of five prospective studies.

Menopausal hormone therapy does not influence lung cancer risk: results from the California Teachers Study.

Fumonisin B1 as a urinary biomarker of exposure in a maize intervention study among South African subsistence farmers.

Use of the predictive sugars biomarker to evaluate self-reported total sugars intake in the Observing Protein and Energy Nutrition (OPEN) study.

Association between levels of C-reactive protein and leukocytes and cancer: three repeated measurements in the Swedish AMORIS study.

The analysis of depression and subsequent cancer risk in Taiwan.

Disclosing individual CDKN2A research results to melanoma survivors: interest, impact, and demands on researchers.

Body size, physical activity, and risk of triple-negative and estrogen receptor-positive breast cancer.

Scientific bias arising from sampling, selective recruitment, and attrition: the case for improved reporting.

Year: 2011 Volume: 20 Issue: 2

Year: 2011 Volume: 20 Issue: 1

Year: 2010 Volume: 19

Year: 2009 Volume: 18

Year: 2008 Volume: 17

Year: 2007 Volume: 16

Year: 2006 Volume: 15

Year: 2005 Volume: 14

Year: 2004 Volume: 13

Year: 2003 Volume: 12

The effects of body mass index on changes in prostate-specific antigen levels and prostate volume over 15 years of follow-up: implications for prostate cancer detection.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wallner, Lauren P. Morgenstern, Hal McGree, Michaela E. Jacobson, Debra J. St Sauver, Jennifer L. Jacobsen, Steven J. Sarma, Aruna V.
Spatial Coverage	Minnesota
Description	Country affiliation: United States Author Affiliation: Wallner LP ( Department of Urology, University of Michigan, Ann Arbor, MI, USA. lauren.p.wallner@kp.org)
Abstract	OBJECTIVE: To investigate the association of body mass index (BMI) and BMI change with change in prostate-specific antigen (PSA) level and to assess the possible roles of PSA hemodilution and prostate volume in explaining the obesity and PSA association. METHODS: In 1990, a randomly selected cohort of Caucasian men, aged 40 to 79 years, from Olmsted County, Minnesota, completed questionnaires ascertaining demographic characteristics, current medical conditions, and medications biennially, with a subset undergoing blood draws and clinical examinations. Linear mixed models were used to predict annual changes and intercepts of individual changes in BMI, PSA, prostate volume, plasma volume, and PSA mass, adjusting for age in 545 men with at least 2 serial PSA, BMI, and prostate volume measurements. RESULTS: Baseline BMI was inversely associated with the annual percent change in PSA, adjusting for age, baseline PSA, and prostate volume and for the rates of change in BMI and prostate volume (ß=-0.003, 95% CI: -0.006 to -0.0003). Baseline obesity was positively associated with mean baseline levels and the rate of change in prostate volume (P=0.002) and plasma volume (both P<0.001) but was not associated with either the mean baseline values or the rate of change in PSA mass. CONCLUSIONS: Baseline obesity was associated with baseline PSA and prostate volume and with the rate of change in PSA over 15 years of follow-up. IMPACT: The inverse association of obesity with prostate cancer diagnosis may be at least partly due to detection bias, which is due to larger prostate volumes and PSA hemodilution in obese men.
File Format	HTM / HTML
ISSN	10559965
e-ISSN	15387755
DOI	10.1158/1055-9965.EPI-10-1006
Journal	Cancer Epidemiology Biomarkers & Prevention
Issue Number	3
Volume Number	20
Language	English
Publisher	American Association for Cancer Research
Publisher Date	2011-03-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Cancer epidemiology Obesity Epidemiology Prostate-specific Antigen Blood Prostate Anatomy & Histology Prostatic Neoplasms Diagnosis Body Composition Body Mass Index Cohort Studies Longitudinal Studies Minnesota Pathology Questionnaires Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Epidemiology Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Relationship between prostate-specific antigen, age, and body mass index in a prostate cancer screening population.

The Effects of Body Mass Index on Changes in Prostate-Specific Antigen Levels and Prostate Volume over 15-years of Follow-up: Implications for Prostate Cancer Detection

Relationship of body mass, height, and weight gain to prostate cancer risk in the multiethnic cohort.

Obesity and future prostate cancer risk among men after an initial benign biopsy of the prostate.

Serum prostate-specific antigen hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Association of diabetes and body mass index with levels of prostate-specific antigen: implications for correction of prostate-specific antigen cutoff values?

The relation of serum parathyroid hormone and serum calcium to serum levels of prostate-specific antigen: a population-based study.

Body composition, abdominal fat distribution, and prostate-specific antigen test results.

Obesity inversely correlates with prostate-specific antigen levels in a population with normal screening results of prostate cancer in northwestern China

The effects of body mass index on changes in prostate-specific antigen levels and prostate volume over 15 years of follow-up: implications for prostate cancer detection.

Similar Documents

Relationship between prostate-specific antigen, age, and body mass index in a prostate cancer screening population.

The Effects of Body Mass Index on Changes in Prostate-Specific Antigen Levels and Prostate Volume over 15-years of Follow-up: Implications for Prostate Cancer Detection

Relationship of body mass, height, and weight gain to prostate cancer risk in the multiethnic cohort.

Obesity and future prostate cancer risk among men after an initial benign biopsy of the prostate.

Serum prostate-specific antigen hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Association of diabetes and body mass index with levels of prostate-specific antigen: implications for correction of prostate-specific antigen cutoff values?

The relation of serum parathyroid hormone and serum calcium to serum levels of prostate-specific antigen: a population-based study.

Body composition, abdominal fat distribution, and prostate-specific antigen test results.

Obesity inversely correlates with prostate-specific antigen levels in a population with normal screening results of prostate cancer in northwestern China

The effects of body mass index on changes in prostate-specific antigen levels and prostate volume over 15 years of follow-up: implications for prostate cancer detection.