NDLI: Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Baron, D. M. Hochrieser, H. Posch, M. Metnitz, B. Rhodes, A. Moreno, R. P. Pearse, R. M. Metnitz, P.
Spatial Coverage	Europe
Description	Country affiliation: Austria Author Affiliation: Baron DM ( Department of Anaesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Vienna, Austria.); Hochrieser H ( Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.); Posch M ( Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.); Metnitz B ( Austrian Center for Documentation and Quality Management in Intensive Care Medicine, Vienna, Austria.); Rhodes A ( Intensive Care Medicine, St Georges Healthcare NHS Trust and St Georges University of London, St Georges Hospital, London, UK philipp@metnitz.biz andrewrhodes@nhs.net.); Moreno RP ( UCINC, Hospital de São José, Centro Hospitalar de Lisboa Central, EPE, Lisbon, Portugal.); Pearse RM ( Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.); Metnitz P ( Department of Anaesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Vienna, Austria philipp@metnitz.biz andrewrhodes@nhs.net.)
Abstract	BACKGROUND: Retrospective studies suggest that preoperative anaemia is associated with poor outcomes after surgery. The objective of this study was to describe mortality rates and patterns of intensive care resource use for patients with anaemia undergoing non-cardiac and non-neurological in-patient surgery. METHODS: We performed a secondary analysis of a large prospective study describing perioperative care and survival in 28 European nations. Patients at least 16 yr old undergoing in-patient surgery during a 7 day period were included in the study. Data were collected for in-hospital mortality, duration of hospital stay, admission to intensive care, and intensive care resource use. Multivariable logistic regression analysis was performed to understand the effects of preoperative haemoglobin (Hb) levels on in-hospital mortality. RESULTS: We included 39 309 patients in the analysis. Preoperative anaemia had a high prevalence in both men and women (31.1% and 26.5%, respectively). Multivariate analysis showed that patients with severe [odds ratio 2.82 (95% confidence interval 2.06-3.85)] or moderate [1.99 (1.67-2.37)] anaemia had higher in-hospital mortality than those with normal preoperative Hb concentrations. Furthermore, hospital length of stay (P<0.001) and postoperative admission to intensive care (P<0.001) were greater in patients with anaemia than in those with normal Hb concentrations. CONCLUSIONS: Anaemia is common among non-cardiac and non-neurological surgical patients, and is associated with poor clinical outcome and increased healthcare resource use. CLINICAL TRIAL REGISTRATION: NCT01203605 (ClinicalTrials.gov).
File Format	HTM / HTML
ISSN	00070912
e-ISSN	14716771
Journal	British Journal of Anaesthesia
Issue Number	3
Volume Number	113
Language	English
Publisher	Oxford University Press
Publisher Date	2014-09-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Anesthesiology Anemia Epidemiology Hospital Mortality Outcome And Process Assessment (health Care) Statistics & Numerical Data Postoperative Complications Preoperative Period Surgical Procedures, Operative Causality Cohort Studies Comorbidity Critical Care Intensive Care Units Length Of Stay Odds Ratio Prospective Studies Risk Factors Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Anesthesiology and Pain Medicine

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