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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Shen, Fangrong Wang, Lu Yang, Weiwen Chen, Youguo |
| Spatial Coverage | China |
| Description | Country affiliation: China Author Affiliation: Shen F ( Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, 118 Shizi Street, Suzhou, 215006, Jiangsu, China.); Wang L ( Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.); Yang W ( Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, 118 Shizi Street, Suzhou, 215006, Jiangsu, China.); Chen Y ( Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, 118 Shizi Street, Suzhou, 215006, Jiangsu, China.) |
| Abstract | PURPOSE: Amniotic fluid embolism (AFE) is an unpredictable and unpreventable complication of maternity. The presentation may range from relatively subtle clinical events to sudden maternal cardiac arrest. However, the neglected diagnosis of non-classical form of AFE (atypical AFE) is very common. The aim of this study was to examine population-based regional data from Suzhou, China. Based on the analysis of all available case reports, we put forward an outline of atypical AFE and investigate whether any variation identified could be ascribed to methodology. METHODS: Retrospective study from January 2004 to December 2013, 53 cases was identified from the database of Center for Disease Control (CDC) in the city of Suzhou. We investigated the presentations of atypical AFE and maternal characteristics with potential factors underlying AFE. Multiple-regression analysis was used to calculate adjusted odds ratios (ORs) and 95 % confidence intervals (CIs). RESULTS: The incidence of AFE was 6.91 per 100,000 deliveries (53/766,895). Seventeen deaths occurred, a mortality rate of 32 %. Atypical AFE may as the earlier stage or mild form of AFE, there was no death case in the study with timely remedy. The atypical AFE appear is obstetric hemorrhage and/or pulmonary and renal dysfunction postpartum. Hyperfibrinolysis and coagulopathy may the early laboratory findings of atypical AFE. Atypical and classical AFE shared the same risks, such as advanced maternal age, placental abnormalities, operative deliveries, eclampsia, cervical lacerations, and induction of labor. CONCLUSION: Staying alert to premonitory symptoms of AFE is critical to turn it to a remediable disease. Patient complaints such as breathlessness, chest pain, feeling cold, distress, panic, a feeling of nausea, and vomiting should elicit close attention. The management of a suspected episode of amniotic fluid embolism is generally considered to be supportive. Hysterectomy must be performed if there is further progression of symptoms. Due to advances in acute care, mortality has decreased in recent years, highlighting the importance of early detection and treatment. |
| File Format | HTM / HTML |
| ISSN | 09320067 |
| Issue Number | 2 |
| Volume Number | 293 |
| e-ISSN | 14320711 |
| Journal | Archives of Gynecology and Obstetrics |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2016-02-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Obstetrics Discipline Gynecology Embolism, Amniotic Fluid Ethnology Etiology Pregnancy Complications, Cardiovascular Diagnosis Adolescent Adult China Epidemiology Delivery, Obstetric Adverse Effects Eclampsia Female Humans Incidence Labor, Obstetric Maternal Age Multivariate Analysis Postpartum Period Pregnancy Retrospective Studies Risk Factors Young Adult Journal Article Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Obstetrics and Gynecology |
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