NDLI: Follow-up of coiled cerebral aneurysms at 3T: comparison of 3D time-of-flight MR angiography and contrast-enhanced MR angiography.

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Follow-up of coiled cerebral aneurysms at 3T: comparison of 3D time-of-flight MR angiography and contrast-enhanced MR angiography.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Anzalone, N. Scomazzoni, F. Cirillo, M. Righi, C. Simionato, F. Cadioli, M. Iadanza, A. Kirchin, M. A. Scotti, G.
Description	Country affiliation: Italy Author Affiliation: Anzalone N ( Department of Neuroradiology, Ospedale San Raffaele, Milan, Italy. anzalone.nicoletta@hsr.it)
Abstract	BACKGROUND AND PURPOSE: Our aim was to compare contrast-enhanced MR angiography (CE-MRA) and 3D time-of-flight (TOF) MRA at 3T for follow-up of coiled cerebral aneurysms. MATERIALS AND METHODS: Fifty-two patients treated with Guglielmi detachable coils for 54 cerebral aneurysms were evaluated at 3T MRA. 3D TOF MRA (TR/TE = 23/3.5; SENSE factor = 2.5) and CE-MRA by using a 3D ultrafast gradient-echo sequence (TR/TE = 5.9/1.8; SENSE factor = 3) enhanced with 0.1-mmol/kg gadobenate dimeglumine were performed in the same session. Source images, 3D maximum intensity projection, 3D shaded surface display, and/or 3D volume-rendered reconstructions were evaluated in terms of aneurysm occlusion/patency and artifact presence. RESULTS: In terms of clinical classification, the 2 MRA sequences were equivalent for 53 of the 54 treated aneurysms: 21 were considered fully occluded, whereas 16 were considered to have a residual neck and 16 were considered residually patent at follow-up MRA. The remaining aneurysm appeared fully occluded at TOF MRA but had a residual patent neck at CE-MRA. Visualization of residual aneurysm patency was significantly (P = .001) better with CE-MRA compared with TOF MRA for 10 (31.3%) of the 32 treated aneurysms considered residually patent with both sequences. Coil artifacts were present in 5 cases at TOF MRA but in none at CE-MRA. No relationship was apparent between the visualization of patency and either the size of the aneurysm or the interval between embolization and follow-up. CONCLUSION: At follow-up MRA at 3T, unenhanced TOF and CE-MRA sequences are similarly effective at classifying coiled aneurysms as occluded or residually patent. However, CE-MRA is superior to TOF MRA for visualization of residual patency and is associated with fewer artifacts.
File Format	HTM / HTML
ISSN	01956108
e-ISSN	1936959X
Journal	American Journal of Neuroradiology
Issue Number	8
Volume Number	29
Language	English
Publisher	American Journal of Neuroradiology
Publisher Date	2008-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Neurology Discipline Radiology Embolization, Therapeutic Image Enhancement Imaging, Three-dimensional Intracranial Aneurysm Diagnosis Therapy Magnetic Resonance Angiography Meglumine Analogs & Derivatives Organometallic Compounds Contrast Media Reproducibility Of Results Sensitivity And Specificity Comparative Study Randomized Controlled Trial
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Neurology (clinical)

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