NDLI: Best (but oft-forgotten) practices: designing, analyzing, and reporting cluster randomized controlled trials.

Please wait, while we are loading the content...

Dietary Approaches to Stop Hypertension diet retains effectiveness to reduce blood pressure when lean pork is substituted for chicken and fish as the predominant source of protein.

Global metabolomic profiling targeting childhood obesity in the Hispanic population

Cesarean delivery and metabolic risk factors in young adults: a Brazilian birth cohort study.

A generic coding approach for the examination of meal patterns.

Interaction between BMI and APOE genotype is associated with changes in the plasma long-chain-PUFA response to a fish-oil supplement in healthy participants.

Dietary cholesterol and cardiovascular disease: a systematic review and meta-analysis.

High glycemic index diet as a risk factor for depression: analyses from the Women's Health Initiative.

Harnessing the power of disgust: a randomized trial to reduce high-calorie food appeal through implicit priming.

Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa.

Maternal prepregnancy waist circumference and BMI in relation to gestational weight gain and breastfeeding behavior: the CARDIA study.

Health effects of intermittent fasting: hormesis or harm? A systematic review.

Dietary magnesium and potassium intakes and circulating magnesium are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the EPIC-Norfolk cohort $study^{1},^{2}$

Does fortification of staple foods improve vitamin D intakes and status of groups at risk of deficiency? A United Kingdom modeling study.

Absence of an effect of high nitrate intake from beetroot juice on blood pressure in treated hypertensive individuals: a randomized controlled trial.

Butter increased total and LDL cholesterol compared with olive oil but resulted in higher HDL cholesterol compared with a habitual diet.

Dietary polyamine intake and colorectal cancer risk in postmenopausal women.

Insulin secretion and sensitivity in healthy adults with low vitamin D are not affected by high-dose ergocalciferol administration: a randomized controlled trial.

Vitamin and carotenoid intake and risk of head-neck cancer subtypes in the Netherlands Cohort Study.

Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: results from the TEDDY study.

Milk intake is not associated with low risk of diabetes or overweight-obesity: a Mendelian randomization study in 97,811 Danish individuals.

Maternal vitamin D3 supplementation at 50 µg/d protects against low serum 25-hydroxyvitamin D in infants at 8 wk of age: a randomized controlled trial of 3 doses of vitamin D beginning in gestation and continued in lactation.

Healthy obesity and objective physical activity.

Neuropeptide Y genotype, central obesity, and abdominal fat distribution: the POUNDS LOST trial.

Olive oil consumption and risk of type 2 diabetes in US women.

Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study.

Studying dietary phosphorus intake: the challenge of when a gram is not a gram.

Prospective association between dietary folate intake and skin cancer risk: results from the Supplémentation en Vitamines et Minéraux Antioxydants cohort.

High provitamin A carotenoid serum concentrations, elevated retinyl esters, and saturated retinol-binding protein in Zambian preschool children are consistent with the presence of high liver vitamin A stores.

Eggs and beyond: is dietary cholesterol no longer important?

Introduction to the series 'Best (but Oft-Forgotten) Practices'.

Eating under observation: a systematic review and meta-analysis of the effect that heightened awareness of observation has on laboratory measured energy intake.

Uncertainties of assessing total body vitamin A stores in community settings in low-income countries using the stable-isotope dilution methodology.

Reply to G Lietz et al.

Year: 2015 Volume: 102 Issue: 1

Year: 2015 Volume: 101

Year: 2014 Volume: 100

Year: 2014 Volume: 99

Year: 2013 Volume: 98

Year: 2013 Volume: 97

Year: 2012 Volume: 96

Year: 2012 Volume: 95

Year: 2011 Volume: 94

Year: 2011 Volume: 93

Year: 2010 Volume: 92

Year: 2010 Volume: 91

Year: 2009 Volume: 90

Year: 2009 Volume: 89

Year: 2008 Volume: 88

Year: 2008 Volume: 87

Best (but oft-forgotten) practices: designing, analyzing, and reporting cluster randomized controlled trials.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Brown, Andrew W. Li, Peng Bohan Brown, Michelle M. Kaiser, Kathryn A. Keith, Scott W. Oakes, J. Michael Allison, David B.
Description	Author Affiliation: Brown AW ( Office of Energetics, Nutrition Obesity Research Center, and awbrown@uab.edu dallison@uab.edu.); Li P ( Office of Energetics.); Bohan Brown MM ( Department of Food, Nutrition, and Packaging Sciences, Clemson University, Clemson, SC); Kaiser KA ( Office of Energetics, Nutrition Obesity Research Center, and.); Keith SW ( Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA); Oakes JM ( Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN.); Allison DB ( Office of Energetics, Nutrition Obesity Research Center, and Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL)
Abstract	Cluster randomized controlled trials (cRCTs; also known as group randomized trials and community-randomized trials) are multilevel experiments in which units that are randomly assigned to experimental conditions are sets of grouped individuals, whereas outcomes are recorded at the individual level. In human cRCTs, clusters that are randomly assigned are typically families, classrooms, schools, worksites, or counties. With growing interest in community-based, public health, and policy interventions to reduce obesity or improve nutrition, the use of cRCTs has increased. Errors in the design, analysis, and interpretation of cRCTs are unfortunately all too common. This situation seems to stem in part from investigator confusion about how the unit of randomization affects causal inferences and the statistical procedures required for the valid estimation and testing of effects. In this article, we provide a brief introduction and overview of the importance of cRCTs and highlight and explain important considerations for the design, analysis, and reporting of cRCTs by using published examples.
File Format	HTM / HTML
ISSN	00029165
e-ISSN	19383207
DOI	10.3945/ajcn.114.105072
Journal	American Journal of Clinical Nutrition
Issue Number	2
Volume Number	102
Language	English
Publisher	American Society for Nutrition
Publisher Date	2015-08-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Nutritional Sciences Nutritional Sciences Practice Guidelines As Topic Randomized Controlled Trials As Topic Research Design Statistics As Topic Cluster Analysis Periodicals As Topic Research Support, N.i.h., Extramural
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Best (but oft forgotten) practices: testing for treatment effects in randomized trials by separate analyses of changes from baseline in each group is a misleading approach.

Best (but oft-forgotten) practices: checking assumptions concerning regression residuals.

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

Nutrition trials in critical illness: bigger, faster, stronger.

Nutrition support in surgical oncology.

Better standards for better reporting of RCTs.

Best (but oft-forgotten) practices: the multiple problems of multiplicity-whether and how to correct for many statistical tests.

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies 1

Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature

Best (but oft-forgotten) practices: designing, analyzing, and reporting cluster randomized controlled trials.

Similar Documents

Best (but oft forgotten) practices: testing for treatment effects in randomized trials by separate analyses of changes from baseline in each group is a misleading approach.

Best (but oft-forgotten) practices: checking assumptions concerning regression residuals.

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

Nutrition trials in critical illness: bigger, faster, stronger.

Nutrition support in surgical oncology.

Better standards for better reporting of RCTs.

Best (but oft-forgotten) practices: the multiple problems of multiplicity-whether and how to correct for many statistical tests.

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies 1

Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature

Best (but oft-forgotten) practices: designing, analyzing, and reporting cluster randomized controlled trials.