NDLI: Tolvaptan is successful in treating inappropriate antidiuretic hormone secretion in infants.

Please wait, while we are loading the content...

Year: 2017 Volume: 106

Year: 2016 Volume: 106

Year: 2016 Volume: 105

Year: 2016 Volume: 105 Issue: 12

Year: 2016 Volume: 105 Issue: 11

Year: 2016 Volume: 105 Issue: 10

Year: 2016 Volume: 105 Issue: 9

Year: 2016 Volume: 105 Issue: 8

Year: 2016 Volume: 105 Issue: 7

Suboptimal bonding impairs hormonal, epigenetic and neuronal development in preterm infants, but these impairments can be reversed.

The implementation of systematic pain and sedation management has no impact on outcome in extremely preterm infants.

Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.

Kawasaki disease and cardiovascular risk: a comprehensive review of subclinical vascular changes in the longer term.

Early intervention leads to long-term developmental improvements in very preterm infants, especially infants with bronchopulmonary dysplasia.

Therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy had favourable outcomes at a referral hospital in a middle-income country.

The severity of acute bronchiolitis in infants was associated with quality of life nine months later.

Current views on the diagnosis and management of hypokalaemia in children.

Serious complications in male infant circumcisions in Scandinavia indicate that this always be performed as a hospital-based procedure.

Healthcare professionals approach paediatric fever in significantly different ways and fever phobia is not just limited to parents.

The more things change, the more things stay the same: maternal attitudes 3 to 18 months postpartum.

Inflammation, lipids and aortic intima-media thickness in newborns following chorioamnionitis.

Preterm cranial ultrasound scanning is both feasible and effective in a middle-income country.

The physiologic coupling of sucking and swallowing coordination provides a unique process for neonatal survival.

Tolvaptan is successful in treating inappropriate antidiuretic hormone secretion in infants.

Maternal drug or alcohol abuse is associated with decreased head size from mid-pregnancy to childhood.

Autism spectrum disorders before diagnosis: results from routine developmental surveillance at 18 months.

Chronic nonbacterial osteomyelitis may be associated with renal disease and bisphosphonates are a good option for the majority of patients.

Association between neonatal resuscitation and a single nucleotide polymorphism rs1835740.

Longitudinal and subgroup analysis approach to understand early intervention programme outcomes for very preterm infants.

Cystic fibrosis and vitamin D: the quest for more pieces of the puzzle.

Therapeutic hypothermia in middle-income settings: where to now?

Risk factor analysis of parenteral nutrition-associated cholestasis in extremely low birth weight infants.

Skin-to-skin contact is associated with earlier breastfeeding attainment in preterm infants.

Highlights in this issue.

How Zika virus made the transition from being a virtually unknown virus to a high-profile public health threat.

Nurture in the neonatal intensive care unit.

It is important with developmental supportive interventions beyond the NICU period.

Impact of a systematic neonatal pain and sedation protocol.

Revisiting a dilemma: repetitive pain vs. opioid exposures?

Year: 2016 Volume: 105 Issue: 6

Year: 2016 Volume: 105 Issue: 5

Year: 2016 Volume: 105 Issue: 4

Year: 2016 Volume: 105 Issue: 3

Year: 2016 Volume: 105 Issue: 2

Year: 2016 Volume: 105 Issue: 1

Year: 2015 Volume: 104

Year: 2014 Volume: 103

Year: 2013 Volume: 102

Year: 2012 Volume: 101

Year: 2011 Volume: 100

Year: 2010 Volume: 99

Year: 2009 Volume: 98

Year: 2008 Volume: 97

Year: 2007 Volume: 96

Year: 2004 Volume: 93

Tolvaptan is successful in treating inappropriate antidiuretic hormone secretion in infants.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Marx-Berger, Daniela Milford, David V. Bandhakavi, Meenakshi Van't Hoff, William Kleta, Robert Dattani, Mehul Bockenhauer, Detlef
Description	Country affiliation: Switzerland Author Affiliation: Marx-Berger D ( Department of Paediatrics, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland.); Milford DV ( Department of Nephrology, Birmingham Children's Hospital, Birmingham, UK.); Bandhakavi M ( Department of Paediatrics, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.); Van't Hoff W ( Renal Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.); Kleta R ( Renal Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.); Dattani M ( UCL Centre for Nephrology, London, UK.); Bockenhauer D ( Endocrine Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.)
Abstract	AIM: Using fluid restriction to treat the syndrome of inappropriate antidiuretic hormone secretion (SIADH) in infants is potentially hazardous, as fluid intake and caloric intake are connected. Antagonists for the type 2 vasopressin receptor have demonstrated efficacy in adult patients with SIADH, but evidence in children is lacking. We reviewed our experience from two cases in the UK. METHODS: This was a retrospective review of the clinical data on two patients diagnosed with SIADH in infancy and treated with tolvaptan, an oral vasopressin receptor antagonist. RESULTS: Persistent hyponatraemia was noted in both patients in the first month of life and eventually led to SIADH diagnoses. Initial salt supplementation in one patient resulted in severe hypertension, treated with four antihypertensive drugs. Tolvaptan was commenced at two and four months of age, respectively, and was associated with normalisation of plasma sodium values and blood pressure without the need for antihypertensive treatment. There was transient hypernatraemia in one patient, which was normalised with a dose reduction. Tolvaptan was administered by crushing the tablet and mixing it with water. CONCLUSION: Tolvaptan provided effective treatment for SIADH in both infants and could be administered orally.
File Format	HTM / HTML
ISSN	08035253
Issue Number	7
Journal	Acta Paediatrica
Volume Number	105
e-ISSN	16512227
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2016-07-01
Publisher Place	Norway
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Pediatrics, Perinatology and Child Health

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in