NDLI: Cannabis og urinprøver.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Westin, Andreas Austgulen
Description	Country affiliation: Norway Author Affiliation: Westin AA ( Avdeling for klinisk farmakologi, St. Olavs hospital, 7006 Trondheim, Norway. andreas.westin@legemidler.no)
Abstract	BACKGROUND: For what duration may cannabinoids be detected in urine after cessation of cannabis use? Medical literature has been reviewed to shed light on the most important issues regarding excretion and detection of cannabinoids, and how to correctly interpret the findings. MATERIAL AND METHODS: The article is based on the author's experience with interpreting urine drug screening results and on a non-systematic search for relevant literature on pharmacokinetics and urinary excretion of cannabinoids. RESULTS: Cannabis users are usually identified through detection of 11-nor-9-corboxy-Delta9-tetrahydrocannabinol (THCCOOH) in urine. Depending on the extent of use, THCCOOH may be detectable in urine from a few days up to three months after cessation of cannabis use. To correctly differentiate between new intake and residual drug excretion, the urinary THCCOOH concentrations must be measured quantitatively and the interpretation must take into account urine dilution and the time span between the dates of specimen collection. Information about the extent of cannabis use and the potential sanctions involved, may influence on how results are interpreted. INTERPRETATION: Differentiating new cannabis intake from residual excretion can be difficult in chronic users. The most precise interpretations are achieved through an open dialogue between client, clinician and laboratory.
File Format	HTM / HTML
ISSN	00292001
e-ISSN	08077096
Journal	Tidsskrift for Den norske legeforening
Issue Number	6
Volume Number	131
Language	Norwegian
Publisher	Norwegian Medical Association
Publisher Date	2011-03-18
Publisher Place	Norway
Access Restriction	Open
Subject Keyword	Discipline Medicine Cannabinoids Urine Marijuana Abuse Substance Abuse Detection Chemistry Pharmacokinetics Creatinine Dronabinol Analogs & Derivatives Metabolism Marijuana Smoking Time Factors
Alternative Title	Cannabis and urine samples
Content Type	Text
Resource Type	Article
Subject	Medicine

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