NDLI: Immune reconstitution associated hypercalcemia.

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Immune reconstitution associated hypercalcemia.

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Immune reconstitution associated hypercalcemia.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Tsao, Yu-Tzu Wu, Yi-Chang Yang, Cheng-Shu Lin, Ying-Tsun
Description	Country affiliation: Taiwan Author Affiliation: Tsao YT ( Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan. tsaoyutzu@gmail.com)
Abstract	The emergence of highly active antiretroviral therapy using combinations of reverse transcriptase and protease inhibitors ushered the dawn of a new era in management of human immunodeficiency virus infection. Immune reconstitution inflammatory syndrome is an adverse consequence of the restoration of pathogen-specific immune responses during the early phase of antiretroviral therapy. Pre-existing subclinical or opportunistic infections become apparent or even 'worse' as host immunological inflammatory responses are 'switched on'. Major reductions in plasma viral load were associated with substantial increases in circulating CD4 T-cell lymphocyte counts and restoration of immune function. The rapid reversal in immune function gives rise to paradoxical therapeutic reaction by rebuilding host immune responses. Herein, a hidden culprit responsible for tuberculosis-associated immune reconstitution characterized by severe hypercalcemia and acute renal failure is reported, illustrating the compounded therapeutic strategy in AIDS patients.
File Format	HTM / HTML
ISSN	07356757
Issue Number	5
Volume Number	27
e-ISSN	15328171
Journal	The American Journal of Emergency Medicine
Language	English
Publisher	Elsevier
Publisher Date	2009-06-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Emergency Discipline Medicine Antiretroviral Therapy, Highly Active Hiv Infections Drug Therapy Immunology Hiv-1 Hypercalcemia Immune Reconstitution Inflammatory Syndrome Chemically Induced Adult Humans Diagnosis Male Viral Load Case Reports Journal Article
Content Type	Text
Resource Type	Article Case study
Subject	Emergency Medicine

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