NDLI: Bioinspired patterning with extreme wettability contrast on TiO2 nanotube array surface: a versatile platform for biomedical applications.

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Bioinspired patterning with extreme wettability contrast on TiO2 nanotube array surface: a versatile platform for biomedical applications.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Lai, Yuekun Lin, Longxiang Pan, Fei Huang, Jianying Song, Ran Huang, Yongxia Lin, Changjian Fuchs, Harald Chi, Lifeng
Description	Author Affiliation: Lai Y ( Physikalisches Institute and Center for Nanotechnology (CeNTech), Westfälische Wilhelms-Universität Münster, Münster D-48149, Germany)
Abstract	Binary wettability patterned surfaces with extremely high wetting contrasts can be found in nature on living creatures. They offer a versatile platform for microfluidic management. In this work, a facile approach to fabricating erasable and rewritable surface patterns with extreme wettability contrasts (superhydrophilic/superhydrophobic) on a TiO2 nanotube array (TNA) surface through self-assembly and photocatalytic lithography is reported. The multifunctional micropatterned superhydrophobic TNA surface can act as a 2D scaffold for site-selective cell immobilization and reversible protein absorption. Most importantly, such a high-contrast wettability template can be used to construct various well-defined 3D functional patterns, such as calcium phosphate, silver nanoparticles, drugs, and biomolecules in a highly selective manner. The 3D functional patterns would be a versatile platform in a wide range of applications, especially for biomedical devices (e.g., high-throughput molecular sensing, targeted antibacterials, and drug delivery). In a proof-of-concept study, the surface-enhanced Raman scattering and antibacterial performance of the fabricated 3D AgNP@TNA pattern, and the targeted drug delivery for site-specific and high-sensitivity cancer cell assays was investigated.
File Format	HTM / HTML
ISSN	16136810
Issue Number	17
Journal	Small
Volume Number	9
e-ISSN	16136829
Language	English
Publisher	Wiley-VCH
Publisher Date	2013-09-09
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Nanotechnology Nanotubes Chemistry Titanium Wettability Nanotechnology Surface Properties Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Medicine Biomaterials Engineering Biotechnology

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