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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Frikha, Faten Snoussi, Mouna Bahloul, Zouhir |
| Spatial Coverage | Tunisia |
| Description | Country affiliation: Tunisia Author Affiliation: Frikha F ( Department of Internal Medicine, Hospital of Hedi Chaker, 3029 Sfax, Tunisia.) |
| Abstract | Celiac disease (CD) is a chronic digestive disease that results in hypersensitivity to the gliadin fraction of Gluten. Malabsorption syndrome may be responsible for weight loss, diarrhea, osteomalacia, and vitamins deficiency. Herein we report a patient with coeliac disease (CD) who presented with osteomalacia and psoriasis without classical symptoms of CD. A 25-year-old North African Tunisian white woman was admitted to the hospital because of a 1-year history of bone pain, weight loss and weakness. She had cutaneous psoriasis on dermatologic examination. She had also anemia, hypocalcemia and pathological fracture. She was diagnosed to have osteomalacia on the basis of clinical, biological and radiological findings. Further investigations revealed the presence of antiglutaminase antibodies, and histopathologic findings of the duodenal biopsy were consistent with celiac disease. The patient showed a fast response to gluten-free diet, and full recovery with calcium and vitamin D replacement. Coeliac disease is frequently misdiagnosed leading to major complications such as osteolamacia. In the other hand, osteomalacia can still be the presenting feature of undiagnosed celiac disease. Association between osteomalacia and cutaneous psoriasis is rarely reported. |
| File Format | HTM / HTML |
| e-ISSN | 19378688 |
| Journal | Pan African Medical Journal |
| Volume Number | 11 |
| Language | English |
| Publisher | African Field Epidemiology Network |
| Publisher Date | 2012-01-01 |
| Publisher Place | Uganda |
| Access Restriction | Open |
| Subject Keyword | Discipline Medicine Celiac Disease Diagnosis Osteomalacia Psoriasis Complications Diagnosis, Differential Tunisia |
| Content Type | Text |
| Resource Type | Article Case study |
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