NDLI: Hepatitis C virus and human immunodeficiency virus coinfection among attendants of voluntary counseling and testing centre and HIV follow up clinics in Mekelle Hospital.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hadush, Haftom Gebre-Selassie, Solomon Mihret, Adane
Spatial Coverage	Ethiopia
Description	Country affiliation: Ethiopia Author Affiliation: Hadush H ( Department of Microbiology, Immunology and Parasitology, School of Medicine, Wollega University, P.O. Box 395, Nekemte, Ethiopia.)
Abstract	INTRODUCTION: Hepatitis C virus remains a large health care burden to the world. HIV and HCV coinfection is major global health concern worldwide. However, there is limited information on the prevalence of HCV/HIV co-infection in Ethiopia. The aim of the study was to assess the magnitude of HIV/HCV coinfection and the potential risk factors in attendants of voluntary counseling and testing centre and HIV follow up clinics of Mekelle hospital. METHODS: A cross sectional seroprevalence survey of HCV infection was carried out on 300 HIV negative and positive subjects attending voluntary counseling and testing (VCT) center and HIV follow up clinics of Mekelle hospital, Ethiopia from December 2010-February 2011. Serum samples were tested for anti-HCV antibodies using immunochromatographic test. RESULTS: Of the 300 study participants, 126(42%) were HIV negative and 174(58%) HIV seropositive from VCT and HIV follow up clinics, respectively. The overall anti-HCV prevalence was 18(6.0%). There were no significant differences in HCV seroprevalence among the different categories of age and sex (p> 0.05). Of the 174 persons with HIV, 16 (9.2%) cases had antibodies to HCV, where as among 126 HIV negative subjects 2 (1.58%) were HCV seropositive (p= 0.006, OR= 6.28, 95% CI= 1.42-27.82). CONCLUSION: Accordingly, there was a significant difference in sero-positivity of HCV between HIV positive and HIV negative participants. No apparent risk factor that caused HCV infection was inferred from this study.
File Format	HTM / HTML
e-ISSN	19378688
DOI	10.11604/pamj.2013.14.107.2302
Journal	Pan African Medical Journal
Volume Number	14
Language	English
Publisher	African Field Epidemiology Network
Publisher Date	2013-01-01
Publisher Place	Uganda
Access Restriction	Open
Subject Keyword	Discipline Medicine Coinfection Hiv Infections Complications Epidemiology Hepatitis C, Chronic Aids Serodiagnosis Adolescent Child, Preschool Counseling Cross-sectional Studies Ethiopia Infant Prospective Studies Seroepidemiologic Studies
Content Type	Text
Resource Type	Article

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