NDLI: Dyslipidaemia as a risk factor in the occurrence of stroke in Nigeria: prevalence and patterns.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Olamoyegun, Michael Adeyemi Akinlade, Akinyele Taofiq Fawale, Michael Bimbola Ogbera, Anthonia Okeoghene
Description	Country affiliation: Nigeria Author Affiliation: Olamoyegun MA ( Department of Internal Medicine, Endocrinology, Diabetes & Metabolism Unit, LAUTECH Teaching Hospital, and College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.); Akinlade AT ( Department of Medicine, General Hospital, Odan, Lagos, Lagos State, Nigeria.); Fawale MB ( Department of Medicine, Obafemi Awolowo University Teaching Hospital Complex, and Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.); Ogbera AO ( Department of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos state.)
Abstract	INTRODUCTION: Stroke is a major public health problem worldwide. Hypertension, diabetes mellitus, dyslipidaemia and smoking are some of the common modifiable risk factors in the occurrence of stroke. Therefore, this study was designed to assess the prevalence and patterns of dyslipidaemia among individuals with acute stroke. METHODS: This is a retrospective descriptive cross-sectional study, carried out in the Departments of Medicine at the LAUTECH Teaching hospital, Ogbomoso and General Hospital, Orile-Agege, Lagos, South-West, Nigeria, over a 18-month period between September 2012 and February 2014. One hundred and six (106) patients with acute stroke confirmed with computed tomography (CT) brain scan were recruited. Clinical features, risk factors, lipid profiles and stroke patterns were identified. RESULTS: Mean age was significantly higher in ischaemic stroke compared to haemorrhagic (64.08±10.87 Vs, 56.21±12.38years, p=0.001). There was slight male preponderance in both stroke types (1.3:1). Out of 106 patients, 65 (61.3%) had ischaemic stroke, 38 (35.8%) intracerebral haemorrhage and 3 (2.9%) with subarachnoid haemorrhage. Dyslipidaemia is the most frequent risk factor (85.9%), followed by hypertension (66.0%) and diabetes mellitus (15.1%). Dyslipidaemia was significantly higher in the ischaemic stroke compared to haemorrhagic. Reduced HDL-cholesterol is the most prevalent fraction of lipid abnormalities (74.5%). CONCLUSION: Dyslipidaemia, particularly low HDL-C, was the most frequent risk factor in our patients with stroke. Hence, prevention of dyslipidaemia as well as other risk factors is key to reducing the burden of stroke in our country.
File Format	HTM / HTML
e-ISSN	19378688
Journal	Pan African Medical Journal
Volume Number	25
Language	English
Publisher	African Field Epidemiology Network
Publisher Date	2016-01-01
Publisher Place	Uganda
Access Restriction	Open
Content Type	Text
Resource Type	Article

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