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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Handa, Mariko Ichinohe, Tatsuya Kaneko, Yuzuru |
| Description | Country affiliation: Japan Author Affiliation: Handa M ( Research Associate, Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan. mhanda@tdc.ac.jp) |
| Abstract | PURPOSE: The purpose of this study was to investigate the effect of changes in partial pressure of arterial CO(2) (PaCO(2)) on oral tissue blood flow. MATERIALS AND METHODS: Twenty male tracheotomized Japan white rabbits were anesthetized with isoflurane (ISO) or propofol (PROP) under mechanical ventilation. Observed variables included heart rate, blood pressure, common carotid artery blood flow (CBF), and tissue blood flow of the mandibular bone marrow (BBF), the masseter muscle (MBF), and the mandibular periosteum (PBF). After completion of experimental preparation, CO(2) was added to inspired gas to change the inspired CO(2) tension. Measurements were performed with end-tidal CO(2) tension (ETCO(2)) maintained at 30, 40, 50, and 60 mmHg. RESULTS: Heart rate in both groups gradually decreased with increasing ETCO(2). In contrast, both systolic and diastolic arterial pressures gradually increased with increasing ETCO(2). Both CBF and BBF increased and MBF decreased with increasing ETCO(2). PBF showed no change throughout the experiment. A positive relationship was observed between CBF and BBF; in contrast, a negative relationship was observed between CBF and MBF. CONCLUSION: Changes in PaCO(2) may induce a redistribution of oral tissue blood flow during both ISO and PROP anesthesia. |
| File Format | HTM / HTML |
| ISSN | 02782391 |
| Issue Number | 9 |
| Volume Number | 66 |
| e-ISSN | 15315053 |
| Journal | Journal of Oral and Maxillofacial Surgery |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2008-09-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Medicine__semicolon__otorhinolaryngology__semicolon__surgery Bone Marrow Blood Supply Carbon Dioxide Blood Mandible Masseter Muscle Periosteum Adaptation, Physiological Anesthetics, Intravenous Pharmacology Animals Blood Gas Analysis Blood Pressure Heart Rate Isoflurane Male Partial Pressure Propofol Rabbits Regional Blood Flow Statistics, Nonparametric Comparative Study Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Oral Surgery Otorhinolaryngology Surgery |
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