Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Luo, Qiong Li, Jingjing Cui, Xiaoyan Yan, Jun Zhao, Qihan Xiang, Chunyan |
| Description | Author Affiliation: Luo Q ( Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, Hubei, PR China. Electronic address: drluoqiong@sina.com.); Li J ( Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, Hubei, PR China.); Cui X ( Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, Hubei, PR China.); Yan J ( Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, Hubei, PR China.); Zhao Q ( Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, Hubei, PR China.); Xiang C ( Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, Hubei, PR China.) |
| Abstract | ETHNOPHARMACOLOGICAL RELEVANCE: Lycium barbarum, a Solanaceous defoliated shrubbery, has been used as a kind of traditional Chinese herbal medicines for thousands of years. Lycium barbarum polysaccharide (LBP) is the main bioactive component of Lycium barbarum. The aim of this study was to investigate the radioresistant effect of LBP on the damage of male rats' reproductive system and spermatogenic cells caused by low-dose (60)Co-γ irradiation. MATERIALS AND METHODS: Male rats were randomly divided into 7 groups and treated with irradiation and/or LBP: normal control group, irradiation control group 1, irradiation control group 2, irradiation control group 3, LBP + irradiation group 1, LBP + irradiation group 2, and LBP + irradiation group 3. RESULTS: It is found that mating function and testis organ coefficient in LBP + irradiation groups were significantly better than that of the corresponding irradiation control groups. LBP significantly up-regulates the expression of Bcl-2 while down-regulating the expression of Bax. And LBP also plays an important role in prevention mitochondrial membrane potential decrease. In addition, LBP can significantly reduce spermatogenic cells apoptosis. CONCLUSION: LBP has obvious protective effect on the male rats' reproductive function and spermatogenic dysfunction induced by irradiation. |
| File Format | HTM / HTML |
| ISSN | 03788741 |
| Issue Number | 1 |
| Volume Number | 154 |
| e-ISSN | 18727573 |
| Journal | Journal of Ethnopharmacology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-05-28 |
| Publisher Place | Ireland |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Ethnopharmacology Drugs, Chinese Herbal Pharmacology Gamma Rays Adverse Effects Genitalia, Male Drug Effects Spermatozoa Animals Apoptosis Physiology Female Pathology Male Membrane Potential, Mitochondrial Proto-oncogene Proteins C-bcl-2 Metabolism Rats, Wistar Sexual Behavior, Animal Bcl-2-associated X Protein Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Drug Discovery Pharmacology |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|