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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Cordeiro, Lucimara M. C. de Oliveira, Simone M. Buchi, Dorly F. Iacomini, Marcello |
| Description | Country affiliation: Brazil Author Affiliation: Cordeiro LM ( Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, CP 19.046, CEP 81.531-990, Curitiba, Paraná, Brazil.) |
| Abstract | A structural study of the carbohydrates from Trebouxia sp., the algal symbiont of the lichen Ramalina gracilis demonstrated a galactofuranan-rich heteropolysaccharide, which was predominated by (1-->5)-linked galactofuranosyl units with side-chains in position 6 on approximately 11.0% of the units. The side-chains have very complex branched structures. This polysaccharide showed cell eliciting activity on peritoneal macrophages in vitro at all concentrations tested (1-150 microg/mL), and at 150 microg/mL an increase of 60% of macrophage activation in comparison to the control group was observed. A potential role of these carbohydrates in lichen recognition process is also discussed. |
| File Format | HTM / HTML |
| ISSN | 01418130 |
| Issue Number | 5 |
| Volume Number | 42 |
| e-ISSN | 18790003 |
| Journal | International Journal of Biological Macromolecules |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2008-06-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biochemistry Chlorophyta Chemistry Galactose Lichens Macrophage Activation Drug Effects Macrophages, Peritoneal Polysaccharides Pharmacology Animals Cells, Cultured Ultrastructure Magnetic Resonance Spectroscopy Male Mice Microscopy, Electron, Scanning Isolation & Purification Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Structural Biology Molecular Biology Biochemistry |
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