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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Baba, Daisuke Seiko, Yasuhiro Nakanishi, Takuya Zhang, Hong Arakaki, Atsushi Matsunaga, Tadashi Osaka, Tetsuya |
| Description | Country affiliation: Japan Author Affiliation: Baba D ( School of Advanced Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan.) |
| Abstract | Superparamagnetic and ferromagnetic magnetite nanoparticles, with diameters of approximately 13 and 44 nm, respectively, were synthesized and their uptake amount and heating efficiency were evaluated for application to magnetic hyperthermia. Both nanoparticles had almost the same zeta-potential (+10.2 mV) and hydrodynamic size (â¼1 µm) and there was no significant difference in their uptake amount 18 h after they were added to the medium. After internalization, the ferromagnetic nanoparticles incorporated in human breast cancer cells (MCF-7) showed a higher heating efficiency than the superparamagnetic nanoparticles when an external magnetic field (4 kW, 250 kHz) high enough to produce heat by hysteresis loss was applied, followed by cellular death of MCF-7 with high ferromagnetic nanoparticle content. |
| File Format | HTM / HTML |
| ISSN | 09277765 |
| Volume Number | 95 |
| e-ISSN | 18734367 |
| Journal | Colloids and Surfaces B: Biointerfaces |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2012-06-15 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Chemistry Antineoplastic Agents Pharmacology Breast Neoplasms Drug Therapy Pathology Ferrosoferric Oxide Nanoparticles Chemistry Chemical Synthesis Cell Proliferation Drug Effects Drug Screening Assays, Antitumor Female Humans Particle Size Structure-activity Relationship Surface Properties Temperature Tumor Cells, Cultured Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Colloid and Surface Chemistry Medicine Physical and Theoretical Chemistry Surfaces and Interfaces Biotechnology |
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