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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Noori, Sahar Naqvi, Andleeb Z. Ansari, Wajid H. |
| Description | Country affiliation: India Author Affiliation: Noori S ( Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India.); Naqvi AZ ( Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India. Electronic address: naqviaz@gmail.com.); Ansari WH ( Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India. Electronic address: wajidhusain.chem@gmail.com.); Kabir-ud-Din ( Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India.) |
| Abstract | Herein the results of surface tension measurements on the mixed systems of an amphiphilic drug amitriptyline hydrochloride (AMT) and three anionic bisphosphodiester gemini surfactants having different hydrophobic tails (8, 10, and 12 carbon) are presented. The experimental and ideal critical micelle concentration (cmc and cmcid) values suggest synergism in mixed systems of AMT and 8-2-8/10-2-10 and attractive interaction in AMT-12-2-12 systems. Other parameters evaluated from the data also suggest mixed micellization among the components with almost 50% contribution of surfactants (micellar mole fraction, X1(m), close to 0.5). The X1 values evaluated from Rubingh's model (X1(m)) and Motomura's model (X1(M)) as well as X1(id) values increase with increasing content of surfactants in solution. Adsorption behavior too indicates that the mixed monolayers experience attractive interaction (ß(σ)) which vary in the order: AMT-12-2-12 |
| File Format | HTM / HTML |
| ISSN | 09277765 |
| Volume Number | 115 |
| e-ISSN | 18734367 |
| Journal | Colloids and Surfaces B: Biointerfaces |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-03-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Chemistry Models, Theoretical Quaternary Ammonium Compounds Chemistry Surface-active Agents Anions Cations Hydrophobic And Hydrophilic Interactions Magnetic Resonance Spectroscopy Micelles Solutions Spectrophotometry, Ultraviolet Surface Tension Chemical Synthesis Temperature Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Colloid and Surface Chemistry Medicine Physical and Theoretical Chemistry Surfaces and Interfaces Biotechnology |
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