NDLI: Cellulose triacetate films obtained from sugarcane bagasse: Evaluation as coating and mucoadhesive material for drug delivery systems.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ribeiro, Sabrina Dias Guimes, Rodrigues Filho Meneguin, Andréia Bagliotti Prezotti, Fabíola Garavello Boni, Fernanda Isadora Cury, Beatriz Stringhetti Ferreira Gremião, Maria Palmira Daflon
Description	Author Affiliation: Ribeiro SD ( Federal University of Uberlândia, Chemistry Institute, Uberlândia, Minas Gerais, Brazil); Guimes RF ( Federal University of Uberlândia, Chemistry Institute, Uberlândia, Minas Gerais, Brazil. Electronic address: guimes.rodriguesfilho@gmail.com.); Meneguin AB ( State University Paulista Júlio de Mesquita Filho, Araraquara, São Paulo, Brazil. Electronic address: abagliottim@hotmail.com.); Prezotti FG ( State University Paulista Júlio de Mesquita Filho, Araraquara, São Paulo, Brazil. Electronic address: fasuecia@yahoo.com.br.); Boni FI ( State University Paulista Júlio de Mesquita Filho, Araraquara, São Paulo, Brazil. Electronic address: boni.fernanda@gmail.com.); Cury BS ( State University Paulista Júlio de Mesquita Filho, Araraquara, São Paulo, Brazil. Electronic address: curybsf@fcfar.unesp.br.); Gremião MP ( State University Paulista Júlio de Mesquita Filho, Araraquara, São Paulo, Brazil. Electronic address: pgremiao@uol.com.br.)
Abstract	Cellulose triacetate (CTA) films were produced from cellulose extracted from sugarcane bagasse. The films were characterized using scanning electron microscopy (SEM), water vapor permeability (WVP), mechanical properties (MP), enzymatic digestion (ED), and mucoadhesive properties evaluation (MPE). WVP showed that more concentrated films have higher values; asymmetric films had higher values than symmetric films. MP showed that symmetric membranes are more resistant than asymmetric ones. All films presented high mucoadhesiveness. From the WVP and MP results, a symmetric membrane with 6.5% CTA was selected for the coating of gellan gum (GG) particles incorporating ketoprofen (KET). Thermogravimetric analysis (TGA) showed that the CTA coating does not influence the thermal stability of the particles. Coated particles released 100% of the KET in 24h, while uncoated particles released the same amount in 4h. The results highlight the CTA potential in the development of new controlled oral delivery systems.
File Format	HTM / HTML
ISSN	01448617
Journal	Carbohydrate Polymers
Volume Number	152
e-ISSN	18791344
Language	English
Publisher	Elsevier
Publisher Date	2016-11-05
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Materials Chemistry Polymers and Plastics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in