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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Fan, Wentao Zhang, Shijie Hao, Pan Zheng, Pimiao Liu, Jianzhu Zhao, Xiaona |
| Description | Author Affiliation: Fan W ( College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, PR China.); Zhang S ( Zhengzhou Ninth People's Hospital, Zhengzhou 450053, PR China.); Hao P ( College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, PR China.); Zheng P ( College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, PR China.); Liu J ( Research Center for Animal Disease Control Engineering Shandong Province, Shandong Agricultural University, Tai'an 271018, PR China. Electronic address: Liujz@sdau.edu.cn.); Zhao X ( College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, PR China. Electronic address: zhaoxn@sdau.edu.cn.) |
| Abstract | In this study, we evaluated structure characterization and immunomodulatory activity of polysaccharides from Astragalus aboriginum Richardson (RAPS), Atractylodes macrocephala Koidz (RAMPS) and Rumia seseloides Hoffm (RSPS) in vitro on chicken macrophage. We found that molecular weight of RAPS and RAMPS was 122.4 and 109.4kDa higher than 64.71kDa of RSPS. Glucose occupied 83.95% and 66.39% in RAPS and RAMPS, respectively. RSPS mainly contained glucose and galacturonic acid, which accounted for 32.35% and 29.25%, respectively. The NMR results displayed that RAPS and RAMPS contained ß- glucose, ß-galactose, and ß-galacturonic acid. The backbone was 1â6 linked glucose. RSPS showed at least six monosaccharide response signals. In vitro experiment, the results showed that RAPS at dosage of 15.62µgmL(-1) exhibited significant immunological on chicken macrophage compared to RAMPS and RSPS. Interestingly, costimulatory molecules levels in RSPS group were higher than that of RAPS, which may associated with the special structure of RSPS. |
| File Format | HTM / HTML |
| ISSN | 01448617 |
| Journal | Carbohydrate Polymers |
| Volume Number | 153 |
| e-ISSN | 18791344 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-11-20 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Materials Chemistry Polymers and Plastics |
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